Calculate appropriate quantities of each ingredient and create a worksheet. (You may create your own lot numbers and expiry dates.) Calculate the dose and write directions for use as they would appear on the label. Include correct expiry date. Describe the purpose of each excipient in this mixture. What else will you provide the Mother on pick up?
Case Study 2
Acetaminophen Elixir 120 mg/5 mL
During the Covid-19 epidemic, the public were advised high fever was a common side effect of infection and to ensure they had acetaminophen on hand. Because of this, there was a sudden nation-wide shortage of commercial liquid acetaminophen. The local Doctor asked if you could compound a mixture for a young child with otitis media as the Mother cannot find any commercially. The Pharmacist did some research and found the following referenced formula for you to use. The Doctor would like to give 50 mL. The child weighs 16 kg.
Formulation:
Acetaminophen 120 mg
90% ethanol 0.7 mL
Propylene glycol 0.5 mL
Purified water 0.5 mL
Glycerol qs ad 5 mL
Dissolve acetaminophen in ethanol and propylene glycol, add most of the glycerol, add water, adjust to volume with glycerol.
Strength: 120 mg/5 mL
Child dose: 15 mg/kg q4-6h. Maximum 4 doses in 24 hours.
Warnings: Contains 13% alcohol
EUD: As per local guidelines.
Questions:
Calculate appropriate quantities of each ingredient and create a worksheet. (You may create your own lot numbers and expiry dates.)
Calculate the dose and write directions for use as they would appear on the label. Include correct expiry date.
Describe the purpose of each excipient in this mixture.
What else will you provide the Mother on pick up?
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