CH3 CH3 MsCI OMs occurs. The resulting sulfonate esters are reactive in Syi and SN2 reactions since the sulfonate group is a very weak base and is therefore a good leaving group Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions Alcohols react with sulfonyl chlorides to form sulfonate esters. Only the O-H bond of the alcohol is broken in the reaction, and so no inversion of configuration CH3 :0 0: CH3 :CI: CH3 он

When 1,2-cyclohexanediol is dehydrated in the presence of concentrated sulfuric acid, the major product is not an alkene. Instead, you get cyclohexanone. Write a reasonable and detailed mechanism for the dehydration of 1,2-cyclohexanediol to form cyclohexanone. Use curved arrows to show the flow of electrons and draw the structures of all intermediates and byproducts formed in the course of this reaction as well as any alternative resonance structures that will help you to account for the formation of the major product observed in this reaction.

List the appropriate reagents that can be used in places with question marks in the following series of reactions.

Fill in the appropriate reagents for the following reaction:

Starting from cyclohexanol, show how to prepare:    Show all reagents and molecules synthesized along the way after each step. You do not have to use curved arrows.

Complete the following syntheses by filling in the missing structures or reagents! Thank you!

Acetals are often prepared during the synthetic sequence to protect the carbonyl group of an aldehyde or ketone. Such an acetal is not reactive to each of the following reagents except:  a.) LiAlH4    b.) PCC(Collins) c.) H3O+ d.) RMgBr e.) NaOH

The Dess–Martin reaction reacts an alcohol with the Dess–Martin periodinane. The first step displaces one of the acetate groups on the periodinane with the alcohol. A base then deprotonates one of the alpha protons, forming a new carbonyl bond, iodinane and acetic acid. The oxidation stops at this stage to give the aldehyde. Both Swern and Dess–Martin conditions will also convert a secondary alcohol to a ketone. Now apply what has just been discussed. Draw the major organic product.

Choose the best reagents from the list provided below for carrying out the following conversion.  Match the reagent with the step number. HCl (aq), Zn(Hg) KMnO4, H3O+ CH3Cl, AlCl3 HNO3, H2SO4 Cl2, FeCl3 fuming sulfuric acid

The compound shown below has three different types of OH groups, all with different acidities. Show the structureproduced after this compound is treated with different amounts of NaH followed by a methylating reagent. Add a briefexplanation.  3 equivalents of NaH, followed by 3 equivalents of CH3I and heat