Consider a sample of 100 individuals sampled from a population in Hardy-Weinberg equilibrium that are genotyped at a single locus. Of these 100 individuals, 25 individuals are A1A1, 45 are A1A2, and 30 are A2A2. What is the actual (observed) allele frequency of the A1 allele in this sample? (you may use a calculator if needed) O A. 0.325 O B. 0.275 O C. 0.475 O D.0.525
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- A sample of 100 individuals from a population that is dimorphic at the A locus has genotype counts as follows. AA: 30 Aa: 60 aa: 10 a) What are the allele frequencies in the population? b) What are the expected genotype frequencies, if the population were at HardyWeinberg equilibrium? c) Is the proportion of heterozygotes lower or higher than expected at Hardy-Weinberg equilibrium? What deviations from the assumptions of the model would best explain the observed difference?Last year you sampled a population of asters in the Rochester area and the allele frequencies for one locus (region of the genome) were p=0.7, q=0.3. Assuming that the population is in Hardy-Weinberg Equilibrium with respect to that locus, which of the following would you expect when sampling this year? a. 42% of the asters are expected to be homozygous dominant. b. 91% of the asters are expected to be heterozygous. c. 9% of the asters are expected to be homozygous recessive. d. 53% of the asters are expected to be heterozygous.10,000 individuals are sampled from a population and are found to display one of three blood types: AA with 6800 individuals, AB with 2800 individuals and type BB with 400 individuals. a) What is the frequency of each genotype in the population? b) What is the frequency of the A allele? c) What is the frequency of the B allele? d) If the next generation contains 25,000 individuals, how many would have blood type BB, assuming the population is in Hardy-Weinberg Equilibrium?
- Consider a Hardy-Weinburg Equilibrium population with an autosomal locus of 2 alleles, A1 and A2. If P(A1A2) = 8 * P(A1A1), what are the allele frequencies at the locus?If a population is in Hardy-Weinberg equilibrium for the multiple alleles A+, A and a, whose frequencies are p= 0.60 for A+, q= 0.20 for A, and r = 0.20 for a, what percentage of the population is expected to be heterozygous?In a human population, the following data were obtained for numbers of people with each blood type (for 3 alleles, use 3 variables p,q, and r ; Hardy-Weinburg equation becomes (p^2 + q^2 + r^2 +2pq + 2pr + 2qr = 1):Type O – 804Type A – 997Type B – 295Type AB – 177Is this population in Hardy-Weinberg equilibrium? Explain.
- Consider the B locus which has two alleles in a population: B and b. Researchers examined the genotypes several individuals for this locus and obtained the following numbers B/B: 302individuals B/b: 56individuals b/b: 17individuals If the B locus is at Hardy-Weinberg equilibrium, what would the expected number of individuals with the Bb genotype? Round your answer to the closest full number.A sample of 600 individuals from a population is examined for the presence of the HindIII polymorphism in an autsomal Sca gene. There are two alleles of Sca gene, A and a. The results are 14 individuals are AA, 212 are Aa, 374 are aa. Please answer the following questions accordingly? How many alleles are present in the gene pool in the sample population fort he Sca gene? What are the genotype frequencies? What are the frequencies of A and a alleles? What are the expected numbers of the three genotypes, assuming random matings.For a simulated population in AlleleA1 to be in Hardy-Weinberg equilibrium, the mutation rate would need to be set at: A. 0. B. 0.1. C. 0.01. D. 0.001
- While studying the frequency of sickle-cell disease ("sickle cell anemia") in a population living in sub-Saharan Africa, you obtain the following data from a sample of n= 100 people (note that I chose a simpler system for identifying the alleles rather than using "Hb S" for sickle cell allele), which is the actual name and what you used in lab). What is the frequency of the sickle cell allele (b) in the sample below from a human population? Sample Data BB-60 individuals (No sickle cell disease) Bb-30 individuals (No sickle cell disease) bb-10 individuals (Sickle cell disease) 1. 0.25 2. 0.10 3. 0.35 4. 0.60 5. 0.20Pretend that you are comparing the actual genotype distribution for a population with the distribution of genotypes predicted by the Hardy-Weinberg theorem. So you hypothesize that the population is in Hardy-Weinberg equilibrium (i.e. that actual population data fit the Hardy-Weinberg expectations). If you carry out chi-square goodness of fit test and calculate a total chi-square value of 0.03 with 1 degree of freedom (see table), what does this mean?Nieman-Pick Syndrome involves a defective enzyme, sphyngomylinase. It is usually fatal before the age of 3. The defective allele frequency is 0.01 in Ashkenazi populations. Let’s call the healthy allele A, and the lethal allele a. a) What is the frequency of allele A? Assuming Hardy-Weinberg equilibrium, how many people do you expect to have the three genotypes in a population of 10,000? b) AA:_______ c) Aa:________ d) aa:_________