Consider the pedigree in Figure 1. Unless there is evidence to the contrary, assume thaindividuals that have married into the family do not carry the recessive gene for the trait.AaAr3.78101115 16 171314Figure 1. Human pedigree showing four generations. Circles represent females,and squares represent males. Shaded circles and squares represent albinoindividuals.

Question
Asked Aug 25, 2019
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What is the probability of cousins 4 & 5 producing an albino offspring?

Consider the pedigree in Figure 1. Unless there is evidence to the contrary, assume tha
individuals that have married into the family do not carry the recessive gene for the trait.
Aa
Ar
3.
7
8
10
11
15 16 17
13
14
Figure 1. Human pedigree showing four generations. Circles represent females,
and squares represent males. Shaded circles and squares represent albino
individuals.
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Consider the pedigree in Figure 1. Unless there is evidence to the contrary, assume tha individuals that have married into the family do not carry the recessive gene for the trait. Aa Ar 3. 7 8 10 11 15 16 17 13 14 Figure 1. Human pedigree showing four generations. Circles represent females, and squares represent males. Shaded circles and squares represent albino individuals.

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Expert Answer

Step 1

Albinism is usually an autosomal recessive inherited condition. So, it can affect an individual only when two copies of recessive allele will be present.

Pedigree analysis is a process of detecting the lineage of a person or any family and can be used to predict the heredity. It can provide an insight about whether the offspring will be affected by a genetic condition or not.

Step 2

In this case, the mother of the cousin 4 is affected. So, it can be considered that she possessed both recessive alleles to develop albinism. The genotype for the mother can be considered as ‘aa’. Offspring 1, 2, 3 and 4 do not show any sign of albinism, then it can be said that none of them carried the homozygous recessive genes. The genotype of all these offspring can be only Aa. It is because, the father is AA. Now, as no offspring from 1-4 are albino, the genotype of father can never be Aa.

 

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Aoo AN & Aalop A Aa A6 Aa Ae AA AP 470

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Step 3

In the case of cousin 5, the mother belongs to the similar lineage as cousin 4. However, his mother is not an alb...

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