D) transcription E) All of the above 13. Proto-oncogene product causes: A stimulation of cell cycle. B) inhibits cell cycle. C) loss/inactivating mutation causes cancer D) none of the above. 14. The following type of mutation in a proto-oncogene may cause cancer in human: A) Translocation of gene B) Gene amplification C) point mutation within regulatory element. D) Point mutation within gene B) All of the above 15. The following statement is true about a proto-oncogene mutation to induce cell division of a mammalian cell: A proto-oncogene product must have an increased the activity. B) proto-oncogene product must have decreased activity. C) tumor suppressor gene product must have an increased activity. D) proto-oncogene must lose ability to express mRNA. 16. The following statement is true about a tumor suppressor gene mutation to induce cell division of a mammalian cell: A) proto-oncogene product must have decreased activity. tumor suppressor gene product must lose activity. C) tumor suppressor gene product must have an increased activity. D) proto-oncogene must lose ability to express mRNA. 17. Incidence of cancer in human increases with age suggesting that: A) cancer is an infectious disease. B multiple mutations are required to develop cancer. C) cancer gene(s) cannot acquired in lifetime. D) none of the above are 18. Plasmids are important in biotechnology because they are: A a vehicle for the insertion of foreign genes into bacteria. B) recognition sites on recombinant DNA strands. C) surfaces for protein synthesis in eukaryotic recombinants. D) surfaces for respiratory processes in bacteria. E) proviruses incorporated into the host DNA. 19. What is the enzymatic function of restriction enzymes? A) to add new nucleotides to the growing strand of DNA B) to join nucleotides during replication C) to join nucleotides during transcription D) to cleave nucleic acids at specific sites E) to repair breaks in sugar-phosphate backbones 20. What is a cloning vector? A) an enzyme that cuts DNA into restriction fragments B) a DNA probe used to locate a particular gene in the genome an agent, such as a plasmid, used to transfer DNA from an in vitro solution into a living cell D) the laboratory apparatus used to clone genes

D) transcription E) All of the above 13. Proto-oncogene product causes: A stimulation of cell cycle. B) inhibits cell cycle. C) loss/inactivating mutation causes cancer D) none of the above. 14. The following type of mutation in a proto-oncogene may cause cancer in human: A) Translocation of gene B) Gene amplification C) point mutation within regulatory element. D) Point mutation within gene B) All of the above 15. The following statement is true about a proto-oncogene mutation to induce cell division of a mammalian cell: A proto-oncogene product must have an increased the activity. B) proto-oncogene product must have decreased activity. C) tumor suppressor gene product must have an increased activity. D) proto-oncogene must lose ability to express mRNA. 16. The following statement is true about a tumor suppressor gene mutation to induce cell division of a mammalian cell: A) proto-oncogene product must have decreased activity. tumor suppressor gene product must lose activity. C) tumor suppressor gene product must have an increased activity. D) proto-oncogene must lose ability to express mRNA. 17. Incidence of cancer in human increases with age suggesting that: A) cancer is an infectious disease. B multiple mutations are required to develop cancer. C) cancer gene(s) cannot acquired in lifetime. D) none of the above are 18. Plasmids are important in biotechnology because they are: A a vehicle for the insertion of foreign genes into bacteria. B) recognition sites on recombinant DNA strands. C) surfaces for protein synthesis in eukaryotic recombinants. D) surfaces for respiratory processes in bacteria. E) proviruses incorporated into the host DNA. 19. What is the enzymatic function of restriction enzymes? A) to add new nucleotides to the growing strand of DNA B) to join nucleotides during replication C) to join nucleotides during transcription D) to cleave nucleic acids at specific sites E) to repair breaks in sugar-phosphate backbones 20. What is a cloning vector? A) an enzyme that cuts DNA into restriction fragments B) a DNA probe used to locate a particular gene in the genome an agent, such as a plasmid, used to transfer DNA from an in vitro solution into a living cell D) the laboratory apparatus used to clone genes

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 6QP: Although it is well known that X-rays cause mutations, they are routinely used to diagnose medical...

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