Question
Asked Oct 26, 2019
58 views

describe the normal and abnormal metabolic pathways of COPD and describe why/how they are disrupted.

check_circle

Expert Answer

Step 1

COPD (chronic obstructive pulmonary disease) is a lung syndrome that includes both bronchitis (inflammation of bronchial tubes) and emphysema (damaged air sacs). This condition is incurable and damaged lung cannot be reversed back to normal condition.

Step 2

In the metabolic pathway of COPD, it triggers the increase in tumor necrosis factor-alpha (TNFα). An increase in TNFα leads to 3 effects involving decreased anabolism, increased reactive oxygen species and increased catabolism of necrosis factor that contribute to decreasing in contractile proteins that cause muscle wasting.

help_outline

Image Transcriptionclose

Pahuway of Copn COPD TNF 1 Anabolsm Dawage Catabolism J Trackive Nk Anoreia ubn eenislomce Reactire Speues (Ros) atein Sytless Degadahin CUMipatin Acive es e NrG Conkachle tems Neeko memdrae APrtease mRNAlo contractile ptein NFK3 Lnde phr selgn

fullscreen
Step 3

Metabolic abnormalities in the pathway of COPD include an increase in fat mass and loss of muscle mass as depicted in t...

Want to see the full answer?

See Solution

Check out a sample Q&A here.

Want to see this answer and more?

Solutions are written by subject experts who are available 24/7. Questions are typically answered within 1 hour.*

See Solution
*Response times may vary by subject and question.
Tagged in

Science

Biology

Animal Physiology and Biochemistry

Related Biology Q&A

Find answers to questions asked by student like you
Show more Q&A
add
question_answer

Q: Mammalian blood contains the equivalent of 0.15M NaCl. Seawater contains the equivalent of 0.45 M Na...

A: Given:Mammalian blood contains the equivalent of 0.15M NaCl. Seawater contains the equivalent of 0.4...

question_answer

Q: I want to make sure I did part h right.

A: Karyotyping is the process of taking photographs of chromosomal pairs to determine the number of chr...

question_answer

Q: how does MALT protect your body?

A: Any substance (foreign or self) that is capable of provoking an immune response in the body is known...

question_answer

Q: How does ATP power metabolic reactions?

A: Cells require continuous supply of energy for survival, but cell can’t store energy as free energy, ...

question_answer

Q: what is the difference between human DNA and strawberry DNA?

A: DNA is found in every plant and animal cell and decides the characteristics of the organisms.

question_answer

Q: Does KCN enable DCPIP to compete more effieciently?

A: KCN or potassium cyanide is crystalline in nature and has no color. It can easily solubilize in wate...

question_answer

Q: Dichotomous key: d. Since gram-negative bacteria are generally more resistant to antibiotics such as...

A: The dichotomous key has two divisions or classifications. In microbiology, the dichotomous key is de...

question_answer

Q: Two genes, A and X, exhibit incomplete linkage. The frequency of the parental gametes (AX and ax) is...

A: When genes exhibiting different traits are located on the same chromosomes they are said to be linke...

question_answer

Q: Please use the image to answer the question, why are there only 2 bands for each sample?

A: The allele ladder in the PCR result refers to the reference alleles locus. The suspect's DNA (deoxyr...