Drug A is a weak acid that has a pKa value of 4. For the Drug A dissolved in Buffer B, calculate what percentage of Drug A is protonated? Can drug A diffuse freely across cell membrane? The pH for Drug A in Buffer B is 6.6 pH. The concentration is 0.1M

Drug A is a weak acid that has a pKa value of 4. For the Drug A dissolved in Buffer B, calculate what percentage of Drug A is protonated? Can drug A diffuse freely across cell membrane? The pH for Drug A in Buffer B is 6.6 pH. The concentration is 0.1M

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section23.6: Reactions With Acids

Problem 23.8P

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Drug A is a weak acid that has a pKa value of 4. For the Drug A dissolved in Buffer B, calculate what percentage of Drug A is protonated? Can drug A diffuse freely across cell membrane?
The pH for Drug A in Buffer B is 6.6 pH. The concentration is 0.1M

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