Epigenetic changes in gene regulation are caused by _ _ _ _ _ _ _ a. missing nucleotides or chromosomes b. modifications to histones and the DNA, but not the nucleotide sequence itself c. mutations of the nucleotide sequence
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| a. | missing nucleotides or chromosomes | |
| b. | modifications to histones and the DNA, but not the |
|
| c. | mutations of the nucleotide sequence |
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- The role of p53 in normal cells is toa. create cancer-blocking mutations.b. trigger unrestrained cell division.c. detect damaged DNA.d. splice exons together in the correct sequence.What are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequenceWhich of the following is not a possible outcome of changing the epigenetic code? a) exposure of regulatory region b) binding of transcription factors c) altered gene expression d) repositioning of nucleosomes by polymerases
- Post-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translationEpigenetic marks regulate gene expression. Which epigenetic mark is NOT associated with positive gene expression? A. Histone acetylation B. Histone Methylation C. De-methylated DNA D. Methylated DNAThe key to epigenetic regulation is ________. a. controlling accessibility to transcription factors and RNA polymerase binding b. biochemical modification of binding factors c. physical modification of the DNA
- Epigenetic control of gene expressiona. is hereditary. c. adds methyl groups to cytosine.b. locks genes “ON.” d. Two of these_____ is the combination of a seat, elation, another modifications to the histones that allow for changes in DNA winding and unwinding a. Epigentics b. Histone code c. Heterochromatin d. Post translational modificationsTranslational control of gene expression occurs within thea. nucleus.b. cytoplasm.c. nucleolus.d. mitochondria.
- Define Epigenetic changes. Are epigenetic changes the same thing as mutations? Explain why or why not.New drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups from histone Explain how these drugs could affect gene expression to help kill tumor cells.Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA molecules