Even though mutations of aquaporin-3 and aquaporin-4 in the collecting duct have not been described in the literature, if mutationsoccurred that resulted in a reduced number of these aquaporins in thecells of the collecting ducts, how would urine volume and concentrationbe affected? Would ADH be an effective treatment?

Human Physiology: From Cells to Systems (MindTap Course List)
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Author:Lauralee Sherwood
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Chapter14: The Urinary System
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Even though mutations of aquaporin-3 and aquaporin-4 in the collecting duct have not been described in the literature, if mutations
occurred that resulted in a reduced number of these aquaporins in the
cells of the collecting ducts, how would urine volume and concentration
be affected? Would ADH be an effective treatment?

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