Second equivalence point First Third Starting point equivalence point equivalence point Midpoint three [HPO]= [PO ] 14 12 10 Midpoint two [H„PO,j= [HPO?1 8 PH 6. Midpoint one [H„POJ = [H,PO, 4 0.5 1.0 1.5 2.0 2.5 3.0 H* ions dissociated/molecule FIG. 2-18 Titration of a polyprotic acid. The first and second equivalence points for titration of H3PO4 occur at the steepest parts of the curve. The pH at the midpoint of each stage provides the pK value of the corresponding ionization. WPLS See the Animated Figures. 2.

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Chapter15: Fluid And Acid-base Balance
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Glycine hydrochloride (Cl H3N+CH2COOH) is a diprotic acid that contains a carboxylic acid group and an ammonium group and is therefore called an amino acid. It is often used in biochemical buffers. Solve, In analogy with Figure , sketch the titration curve of this diprotic acid.

Second
equivalence
point
First
Third
Starting
point
equivalence
point
equivalence
point
Midpoint three
[HPO]= [PO ]
14
12
10
Midpoint two
[H„PO,j= [HPO?1
8
PH
6.
Midpoint one
[H„POJ = [H,PO,
4
0.5
1.0
1.5
2.0
2.5
3.0
H* ions dissociated/molecule
FIG. 2-18 Titration of a polyprotic acid. The first and second equivalence points for
titration of H3PO4 occur at the steepest parts of the curve. The pH at the midpoint of each
stage provides the pK value of the corresponding ionization. WPLS See the Animated Figures.
2.
Transcribed Image Text:Second equivalence point First Third Starting point equivalence point equivalence point Midpoint three [HPO]= [PO ] 14 12 10 Midpoint two [H„PO,j= [HPO?1 8 PH 6. Midpoint one [H„POJ = [H,PO, 4 0.5 1.0 1.5 2.0 2.5 3.0 H* ions dissociated/molecule FIG. 2-18 Titration of a polyprotic acid. The first and second equivalence points for titration of H3PO4 occur at the steepest parts of the curve. The pH at the midpoint of each stage provides the pK value of the corresponding ionization. WPLS See the Animated Figures. 2.
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