Hemophilia is an X-linked recessive disease. A hemophilic man marries a woman who is not a carrier of the disease. (a) Draw a Punnett square showing the genotypes of their children. (b) What are the chances that their daughters will be carriers of the disease? (c) What percentage of their children are likely to have the disease?

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter20: Chromosomes And Human Genetics
Section: Chapter Questions
Problem 2CT: Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how...
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Hemophilia is an X-linked recessive disease. A hemophilic man marries a woman who is not a carrier of the disease.

(a) Draw a Punnett square showing the genotypes of their children.

(b) What are the chances that their daughters will be carriers of the disease?

(c) What percentage of their children are likely to have the disease?

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Step 1 Introduction

Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden pea plants. Mendel presented his work in a paper entitled “Experiments in plant hybridization” at the meeting of the natural history society of Brunn. Mendel gave various postulates regarding the inheritance of characters and these postulates later became the law of Mendel. The three laws given by Mendel are the law of dominance, the law of segregation, and the law of independent assortment.

Human inheritance can be studied by pedigree analysis. Pedigree is a diagram like a family tree. There are 5 types of human inheritance- X-linked recessive, X-linked dominant, Y-linked, autosomal dominant, and autosomal recessive. 

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