How do we know that viral and bacterial chromosomes most often consist of circular DNA molecules devoid of protein?

Concepts of Biology
1st Edition
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:Samantha Fowler, Rebecca Roush, James Wise
Chapter9: Molecular Biology
Section: Chapter Questions
Problem 14CTQ: How do the linear chromosomes in eukaryotes ensure that its ends are replicated completely?
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How do we know that viral and bacterial chromosomes most
often consist of circular DNA molecules devoid of protein?

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