How might a single base pair difference about 100 bases before the start codon of the CFTR gene cause CF?

Q: What are the two major mechanisms for the repair of double-strand breaks? How do they differ?

A: Deoxyribonucleic acid (DNA) is a double stranded helix, which serves as the hereditary unit for…

Q: How do we know that intergenic exchange occurs in bacteriophages?

A: Bacteriophages are the type of viruses which infects the bacteria and have a DNA or RNA molecule in…

Q: What is a non replicative conservative transposon?

A: Transposons are the DNA segment that is known to move from one location to another within a genome.…

Q: If a mutagen causes bases to be removed from nucleotides withinDNA, what repair system would fix…

A: DNA repair is the process in which certain specialized enzymes within the cell known as DNA repair…

Q: What two molecular mechanisms can result in gene conversion?Do both occur in the double-strand break…

A: A gene is a stretch of nucleotides present in the DNA. DNA or deoxyribonucleic acid is a polymer of…

Q: Explain why mutations occur in the CFTR?

A: The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane…

Q: What is the difference between a transition and a transversion? Which type of base substitution is…

A: There are two different types of mutations with DNA substitutions seen in nature.  These are of two…

Q: What are bacteriophages, and what is unique about their structure?

A: The viruses are considered to be non-living when they are out of the host as they lack cellular…

Q: why the repressor proteins bind with the major groove in the DNA helix?

A: DNA is a double helical structure as described by Watson and crick consisting of two loops that is…

Q: Why can it be said that transcription of thebacteriophage T7 genome requires two enzymes?

A: T7 bacteriophage is a small phage which consists of double stranded DNA with 40 kbp nucleotide. The…

Q: How common is dup15q?

A: Dup15q:- Is characterized by having an extra copy of a portion  of chromosome 15[partial trisomy] in…

Q: How can the CRISPR and pi-cluster loci change overtime?

A: CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat. It is a unique…

Q: Why do A-T base pairs inhibit left-handed DNA formation?

A: The capacity of nucleic acids to guide their own reproduction from monomers makes them unique.…

Q: How long is the CFTR gene and what are the first 20 nucleotides of this gene

A: CFTR Gene- CFTR is a Cystic fibrosis transmembrane conductance regulator. It is a membrane protein…

Q: Why is bacteriophage Mu mutagenic, and whatfeatures are necessary for Mu to insert into DNA?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: How do we know if a genomic DNA sequence contains aprotein-coding gene?

A: Only about 1% of DNA contains protein-coding genes; the remaining 99 percent is noncoding. Noncoding…

Q: What does bacteriophage lambda cause?

A: Viruses that infect bacteria are known as bacteriophages. Lambda phage is an example of a…

Q: what kinds of mutation might lead to splicing errors?

A: In living organisms, the genetic instructions for growth, development, functioning, and reproduction…

Q: . a. What are all the transversions that can be made starting with the codon CGG?b. Which of these…

A: In molecular biology, a point mutation in DNA occurs when a single (two ring) purine (A or G) is…

Q: Which of the following statements about a transversion mutation in the sequence AGC is true?

A: Transversion alludes to a point mutation in DNA in which a solitary (two rings) purine is changed…

Q: How does cdc9-50 cause changes to the DNA

A: A eukarotic cell has several nuclear DNA ligases, DNA ligase I play an important role as a…

Q: Where did the 5' 7-methyl-guanosine caps present on influenza virus messenger RNA (MRNA) transcripts…

A: INTRODUCTION After the invention of the cap structure in several virus mRNAs by us et al. , studies…

Q: What would be the phenotype of an E. coli strain in which the tandem tryptophan codons in the leader…

A: The set of genes controlled by a single promoter or regulatory sequence associated with that…

Q: Why is a short RNA primer needed for replication?

A: The deoxyribonucleic acid (DNA) is the double-stranded molecule that is the genetic material in most…

Q: Why aren’t primary rRNA transcripts present in wild-type E. coli?

A: E.coli is a gram negative, faculatative anaerobic, rod-shaped, coliform bacterium of the genus…

Q: What is the difference in the requirement for a primer in RNA transcription compared to DNA…

A: DNA replication is the biological process of producing two identical replicas of DNA from one…

Q: Why do Tbx5 mutations affect limbs and heart but no other tissues?

A: Introduction Mutation can be defined as the change in the DNA sequence or a structural change in the…

Q: Is transposon a insertion sequence?

A: Introduction: Transposons are also called jumping genes are transposable elements or DNA sequence…

Q: What types of proteins are known to be translated using an alternate start codon?

A: The start codon is the first codon of a messenger RNA transcript translated by a ribosome.

Q: How many tailed bacteriophages are there, and where are they located?

A: According to the question, we have to mention the number of the tailed bacteriophages and where they…

Q: What causes DNA diffrences ?

A:

Q: How can these designed nucleases modify the sequence of genomic DNA?

A: A nuclease is a protein that can break the phosphodiester links between nucleotides in nucleic…

Q: How does somatic recombination differ from alternative splicing of RNA?

A: Recombination of DNA (deoxyribonucleic acid) refers to the formation of new DNA as a result of the…

Q: What processes are involved in bacteriophage assembly?

A: A bacteriophage or phage is a type of virus that infects bacteria, as indicated by the name which…

Q: What is the probability that the palindromic symmetry of the trp repressor target DNA sequence is…

A: Palindromic sequences are the sequences present in the DNA double helix that are read the same from…

Q: what are  bacteriophages? explain the functions of attB and attP sequences.

A: Viruses can be defined as particles of DNA or RNA which do not have a cytoplasm, may or may not have…

Q: How does a transposon differ from an insertion sequence?

A: DNA is the genetic material of all organisms except certain viruses with RNA as genetic material. It…

Q: What happens when one nucleotide pair is lost from themiddle of the coding sequence of a gene?

A: Gene is a stretch of DNA that codes for a particular polypeptide chain.

Q: Does transversion occur, If a purine replaces a pyrimidine, or vice versa ?

A: DNA substitution mutation is a type of mutation in which the nitrogenous bases undergo replacement…

Q: How do these designed nucleases modify the genomic DNA sequence?

A: Designer nucleases functions by targeting a specific DNA sequence with in a genome.

Q: How were the experimentally derived triplet codon assignments verified in studies using…

A: MS2 refers to an icosahedral, single-stranded, positive-sense RNA (ribonucleic acid) virus that…

Q: Which E. coli enzyme is the main replicative polymerase in bacteria that synthesizes the genome?

A: Replication is the process by which new DNA strands are duplicated from the existing DNA strands. It…

Q: What is the difference between a recombinant protein and a native protein? Why is it that some…

A: Proteins are the most abundant organic molecules of the living system. They have significant role in…

Q: What is the nature of the prion mutation that leads to extreme sensitivity to prion disease?

A: A misfolded protein can be defined as a protein that cannot get back to its normal native state due…