How to reverse a frame-shift mutation caused by adding one nucleotide base?

Q: What is central dogma of molecular genetics? How does it work ?

A: The Central Dogma was first proposed in 1958 by Francis Crick. He was also the discoverer of the…

Q: What are frameshift mutations with an example

A: Gene mutations are rare and random changes in DNA sequence which result in alteration of polypeptide…

Q: What is a non replicative conservative transposon?

A: Transposons are the DNA segment that is known to move from one location to another within a genome.…

Q: Will an insertion or a deletion of three nucleotides result in a frameshift mutation? Explain why or…

A: The frameshift mutation is the mutation by which the amino acid frame is changed. It is usually…

Q: What are frameshift mutations?

A: Mutations are the alternation or the changes that occur in the DNA. They are variations in codons…

Q: How can we estimate the age of a mutation?

A: Mutation is defined as sudden inheritable change that occurs in the DNA sequence. Mutation occurs…

Q: could Nirenberg and Matthaei have substituted RNA polymerase instead of polynucleotide phosphorylase…

A: The scientist Marshall Nirenberg and Heinrich J. Matthaei designed an experiment to elucidate the…

Q: Can exonuclease be used while producing a recombinant DNA molecule?

A: Introduction: Genetic engineering can be defined as a method to use recombinant DNA or rDNA…

Q: How can a passenger mutation become adriver mutation?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: What are deletion mutation with suitable example?

A: Mutations are the alterations or the changes that occur in the DNA. Mutations are variations in…

Q: What is the difference between a transition and a transversion? Which type of base substitution is…

A: There are two different types of mutations with DNA substitutions seen in nature.  These are of two…

Q: How do base analogs lead to mutations?

A: Base analogues are compounds that have a structure that is substantially close to one of the four…

Q: Briefly explain the frameshift mutation ?

A: Mutation can be defined as the change that occurs in the DNA sequence which is caused by mistake or…

Q: How Linker scanning mutations identify transcription control elements. ?

A: The regulation of gene expression is dependent on many factors. The promoter is the upstream…

Q: What is a A hypomorphic mutation?

A: The change in normal structure or function of a wild type of gene due to alteration in nucleotides,…

Q: How to create precise nucleotide or single-gene mutations or deletions ?

A: Each nucleotide is comprised of sugar, a phosphate gathering, and a nitrogenous base. The sugar is…

Q: If you wanted to study the nature of transcription in yeast under aerobic versus anaerobic…

A: Yeast grows differently under aerobic and anaerobic conditions. To study the nature of transcription…

Q: Why do frameshift mutations generally have more seriousconsequences than missense mutations?

A: Genetic material is nothing but the sequence of nucleic acids which is called as DNA. It contains…

Q: can you help me how to make frameshift mutation and pls explain

A: INTRODUCTION              Frameshift mutation is a process of insertion or deletion of…

Q: What are the silent, misense, nonsense, and frameshift mutations?

A: Mutation is an abrupt change in the DNA sequence and  nucleotide base pairs.  Mutation is caused by…

Q: How to create DNA-sequence alignment ?

A: DNA-Sequence alignment can be defined as the way in which sequences of DNA samples are arranged for…

Q: How is exome sequencing helps in identifying mutations?

A: Exome sequencing refers to the genomic technique in which the sequencing of all the protein-coding…

Q: hat is subcloning

A: Biology is a branch of science. Bio means life and ology means study. Biology is basically the study…

Q: Why do frameshift mutations tend to have a more severe consequence than a missense mutation?

A: Mutation is change in a DNA sequence. Mutations can result from: DNA copying mistakes made during…

Q: How does a mutagen induce mutation ?explain with examples?

A: The DNA is a genetic material- a polynucleotide chain made up of the long chain of A, T, G, and C.…

Q: What is the likely consequence of a frameshift mutation?

A: A mutation occurs/happens when the sequence/structure of DNA is altered. Mutations can occur as a…

Q: How can we use the transposon sequence to find where the mutation occurred in a forward genetic…

A: Forward genetic screes, also termed as forwarding genetics, is a kind of process by which those…

Q: What is codon bias?

A: Deoxyribonucleic acid (DNA) stores the cell’s genetic information and is present in the nucleus of…

Q: How can we identify histone modifications?

A: Histones are the class of proteins which are associated with the DNA in the nucleus and aids in the…

Q: What are at least three molecules involved in DNA transcript proofreading that we reviewed? What are…

A: In humans the DNA is highly coiled to form chromosome. The DNA has many genes which can encodes a…

Q: Among the different types of amino acid substitution (same sense, missense, or nonsense mutations),…

A: Introduction A mutation is a change in the DNA sequence of an organism, either as the result of…

Q: What is frameshift mutation?

A: Mutations are alterations in the genetic material present in the cell of a living organism or of a…

Q: What are base analogs and why are they mutagenic?

A: Introduction :- A mutagen is a substance that can cause DNA mutations by chemical or physical means.…

Q: What is Central Dogma of Molecular Biology and how this concept is used in the development of…

A: Genetically modified organisms are those that have been modified by humans in order to show those…

Q: hat type of  mutation (missense, silent, and non-sense) was introduced in your sequence when G was…

A: A Mutation happens once a deoxyribonucleic acid sequence is broken or modified in such the simplest…

Q: How do you reverse transcribe in RNA?

A: RNA stands for ribonucleic acid. It is a genome in most viruses. It helps in coding, expression of…

Q: make a point mutation and Frameshift mutation

A: point mutation, change within a gene in which one base pair in the DNA sequence is altered. Point…

Q: How can transposons be used in bacterial genetics?

A: Transposable elements are known as stretches of DNA molecules and they can move from one place to…

Q: How base tautomerization causes mutation?

A: Mutations are changes that occurs in the deoxyribonucleic acid (DNA) sequence, either due to…

Q: How many exons has the CFTR gene?

A: Introduction :- The CFTR gene encodes a membrane protein and chloride channel in vertebrates called…

Q: What are frame-shift insertion?

A: Mutations are changes that occurs in the deoxyribonucleic acid (DNA) sequence, either due to…

Q: What is base substitution in Gene Mutations ?

A: What is base substitution in Gene Mutations ?

Q: What is the minimal number of insertions/deletions of nucleotides that would result in a frameshift…

A: A mutation happens when a DNA (deoxyribonucleic acid) gene is broken or modified causing the change…

Q: how many methods for detecting point mutations?

A: A single base pair is changed in a point mutation. Point mutations can also have three different…

Q: What is a silent mutation? Why is the name “silent mutation” a bit of a misnomer?

A: The flow of information in the cell is generally from DNA to RNA to proteins. DNA contains the…

Q: What is substitution RNA editing ?

A: Introduction RNA editing is the process of changing the amino acid sequence of RNA nucleotides. This…

Q: How were the experimentally derived triplet codon assignments verified in studies using…

A: MS2 refers to an icosahedral, single-stranded, positive-sense RNA (ribonucleic acid) virus that…

Q: What is a frameshift error? Does the binding of methionine tRNA to the small subunit help reduce…

A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…

Q: Is insertion a gene mutation?

A: Mutation means sudden changes occur in DNA sequences. The mutation occurs randomly. It also occurs…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.