I have a fill in the blank question. "1) Heterophobic or Homotrophic effects= are changes in affinity due to substrate binding and cooperativity between different subunits. They give Allosteric rate curves their Sigmoid shape. 2) Hetero or Homotrophic effects=are changes in affinity due to binding of an effector to an Allosteric site.  Allosteric sites are usually 3)located outside or inside the active site.  Positive Allosteric effectors (activators) shift the rate curve 4) Left or Right, where Negative effectors shift it 5) right or left.  Positive Allosteric effectors usually stabalize the 6)T or R state.  Negative efftors usually satbalize the R state."

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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I have a fill in the blank question.

"1) Heterophobic or Homotrophic effects= are changes in affinity due to substrate binding and cooperativity between different subunits. They give Allosteric rate curves their Sigmoid shape. 2) Hetero or Homotrophic effects=are changes in affinity due to binding of an effector to an Allosteric site.  Allosteric sites are usually 3)located outside or inside the active site.  Positive Allosteric effectors (activators) shift the rate curve 4) Left or Right, where Negative effectors shift it 5) right or left.  Positive Allosteric effectors usually stabalize the 6)T or R state.  Negative efftors usually satbalize the R state."

 

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