In a large, randomly mating population, the frequency of an autosomalrecessive lethal allele is 0.20. What will the frequency of this allele be inthe next generation if all homozygotes die before reproducing?
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In a large, randomly mating population, the frequency of an autosomal
recessive lethal allele is 0.20. What will the frequency of this allele be in
the next generation if all homozygotes die before reproducing?
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- In a population of a beetle species, you notice that thereis a 3:1 ratio of shiny to dull wing covers. Does this ratioprove that the shiny allele is dominant? (Assume thatthe two states are caused by two alleles of one gene.) Ifnot, what does it prove? How would you elucidate thesituation?Different species of crickets have distinct songs, andthey use these songs for mate recognition. Researcherscrossed two species of Hawaiian crickets (Laupala paranigra and L. kohalensis) whose songs are distinguishedby pulse rate (the number of pulses per second; Shaw etal., Molecular Ecology 16, 2007, 2879–2892.) Then, theymapped QTL in the F2 population derived from thiscross. Six autosomal QTL were detected. The mean traitvalues (pulses per second) at the three genotypic classesin the F2 for each QTL are shown in the table below,where P indicates the L. paranigra allele and K indicatesthe L. kohalensis allele.a. Calculate the additive (A) and dominance (D) effectsand the D/A ratio for each of the six QTL.b. Which of these QTL shows the greatest amount ofdominance?c. Which of these has the largest additive effect?d. The mean pulse rate for L. kohalensis is 3.72, and it is0.71 for L. paranigra. Do all six QTL act in the expecteddirection with the L. kohalensis allele conferring a…Assume that in a certain population of giraffes, dark brown spots are dominant to light brown spots. If the frequency of dark brown giraffes is 56%, what is the frequency of the dark brown allele? Hint: the frequency that is provided is the frequency of a specific phenotype (i.e. not a genotype frequency)
- If albinism occurs in 1/10,000 individuals in a populationat equilibrium and is caused by an autosomal recessiveallele a, calculate the frequency of: The normal dominant allele. In Europe, the frequency of the CF− allele causing therecessive autosomal disease cystic fibrosis is about0.04. Cystic fibrosis causes death before reproductionin virtually all cases.a. Determine values of relative fitness (W) for the unaffected, carrier, and affected genotypes. Assumethat no selective advantage is associated with heterozygosity for the disease allele.b. Given your answer to part (a), determine the average (mean) fitness at birth of the population as awhole with respect to the cystic fibrosis trait (W)and the expected change in allele frequency overone generation (Δq) when measured at the birth ofthe next generation.c. Suppose the European population is at equilibriumfor the frequency of the CF− allele because someheterozygote advantage exists. Recalculate the relative fitness values for the three genotypes underthis assumption. d. The CFTR protein encoded by the CF gene is achloride ion channel. People suffering from cholerahave diarrhea that pumps water and…a population has 700 individuals, 85 of genotype AA, 320of genotype Aa, and 295 of genotype aa. What are thefrequencies of alleles A and a?
- In a population of Hopi indians the autosomal recessive gene for albinism exists at an allele frequency of 0.04. What proportion of these individuals are expected to be heterozygous?For a locus with two alleles (B and b) in a population at riskfrom an infectious neurodegenerative disease, 16 individualshave the genotype BB, 92 individuals have Bb and 12individuals have bb. Use the Hardy-Weinberg equation todetermine whether this population appears to be evolving.What is the frequency of heterozygotes Aa in a randomly mating population if the frequency of the recessive phenotypes (aa) is 0.9?
- If albinism occurs in 1/10,000 individuals in a populationat equilibrium and is caused by an autosomal recessiveallele a, calculate the frequency of: Heterozygotes in the populationIf albinism occurs in 1/10,000 individuals in a populationat equilibrium and is caused by an autosomal recessiveallele a, calculate the frequency of: The recessive mutant alleleIn corn, kernel color is governed by a dominant allele for white color (W) and by a recessive allele for yellow (w). A random sample of 152 kernels from a population that is in Hardy- Weinberg equilibrium reveals that 35 kernels are yellow and 117 kernels are white. What is the frequency of individuals with the homozygous dominant genotype?