In experiments using polymerase chain reactions (PCR), it is often more difficult to amplify through regions of DNA that are high in GC content versus those regions that are either lower in GC content or are AT-rich. Based on your knowledge of DNA structure, explain why.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna
Section: Chapter Questions
Problem 12QP: DNA contains many hydrogen bonds. Are hydrogen bonds stronger or weaker than covalent bonds? What...
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 In experiments using polymerase chain reactions (PCR), it is often more difficult to amplify
through regions of DNA that are high in GC content versus those regions that are either lower in
GC content or are AT-rich. Based on your knowledge of DNA structure, explain why.

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