This was glossed over super quick in class. Extra help would be great BCH 3023C BiochemistryMitochondrial [OAA]In the final step of the citric acid cycle, malate is oxidized to regenerate the oxaloacetatenecessary for the entry of acetyl-CoA into the cycle:malate + NAD oxaloacetate + NADH + H+AG=+30.0 kJ/mol(a) Calculate the equilibrium constant for this reaction at 25 °C.(b) Because AG°' assumes a standard pH of 7.0, the expression for the equilibrium constantdoes not include the expression for H*. The measured concentration of malate in rat livermitochondria is about 0.20 mM when the NAD+/NADH ratio is 10. Calculate theconcentration of oxaloacetate under these conditions.(c) Assuming that the mitochondrion can be modeled as a sphere with a diameter of 2.0 μm,calculate the number of OAA molecules present in a single rat liver mitochondrion.

In a general reaction such as: aA + bB ⇌ cC + dD At equilibrium (steady state), the concentration of…

Answered: In the final step of the citric acid…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter20: Electron Transport And Oxidative Phosphorylation

Section: Chapter Questions

Problem 9P

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