J.F. is a 26-year-old woman in the clinic today for her annual physical examination. As you take her medical history, it becomes apparent that she is quite concerned about her risk for developing breast cancer. Her mother and a maternal aunt both developed breast cancer in their late 40s. J.F. has heard that genetic testing can be done to see whether she carries “breast cancer genes.”   What proportion of breast cancer cases can be attributed to inherited forms?   What other cancer would J.F. be at risk for given the presence of the BRCA1 gene?  How significant is that risk?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
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J.F. is a 26-year-old woman in the clinic today for her annual physical examination. As you take her medical history, it becomes apparent that she is quite concerned about her risk for developing breast cancer. Her mother and a maternal aunt both developed breast cancer in their late 40s. J.F. has heard that genetic testing can be done to see whether she carries “breast cancer genes.”

 

  1. What proportion of breast cancer cases can be attributed to inherited forms?   What other cancer would J.F. be at risk for given the presence of the BRCA1 gene?  How significant is that risk?

 

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