Key: O Normal male Affected male Normal female Affected female 14.1 • • Pedigree 1. FIGURE Key: O Normal male Affected male O Normal female Affected female Carrier female FIGURE • Pedigree 2. 14.2

58 A family has two children with an undiagnosed, very rare neurodevelopmental condition illustrated in the pedigree below. Neither parent is affected and there is no family history of this disorder. The following two questions relate to this pedigree. What is the most likely mode of inheritance for this condition? Select one alternative: Dominant O It is not inherited Recessive X-linked recessive

How many affected females and males does this pedigree show? (2) Who is the proband? (3) How many generations are included?   (4) What kind of inheritance pattern is the disease-causing allele in this pedigree? Why?                 (5) Who have the same genotype as the proband? Why?

If the mother has normal color vision but her daughter has red-green colorblindness, what must be the genotype of the sex chromosomes of the two parents (with respect to red-green vision)

Can you please not type the answer can you write it on a paper

Familial polydactyly is an autosomal dominant trait that results in extra fingers or toes. An affectedwoman and a normal man have a normal son. This couple wants to have 4 more children. What is theprobability that 3 of the children are polydactyl

For the pedigree shown here, give the most likely mode of inheritance.

In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected || IV V 5600 orize 077808 15 10 9 10 CHO વ Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk.…

If individuals II-5 and II-4 have another child, the probability of this child having the polydactyly trait is ___%.

Consider this pedigree showing an autosomal dominant rare disorder. What is the degree of penetrance? Show your work. na оп 16 19 fa 16 R 9X