Let’s suppose you were interested in developing drugs to preventepigenetic changes that may contribute to cancer. What cellularproteins would be the target of your drugs? What possible sideeffects might your drugs cause?

Q: In gene therapy an attempt is made to transfer a "normal" gene into the cells of a person who lacks…

A: Although gene therapy is a newer concept that has yet to be completely investigated, it has been…

Q: Can you please help me by drawing a serie of schematic figures that demonstrates the information in…

A: Proteins undergo post-translational modifications to increase their functional diversity. The…

Q: Genetic instability in the form of point mutations, chromosome rearrangements, and epigenetic…

A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…

Q: Q7

A: Epigenetic changes include all except Change in DNA sequence. Epigenetic changes are modification in…

Q: Why are some chromosomal regions amplified/deleted in a specific manner in certain tumor types?

A: Chromosomal amplification: Chromosomal amplification can be explained as the increase in the amount…

Q: Is the presence of oncogenic Ras necessary for transient inflammatory stimulation to induce chronic…

A: Cancer is disease in which there is uncontrolled proliferation of cell.  In organisms, cell…

Q: The rb gene encodes a protein that inhibits E2F, a transcriptionfactor that activates several genes…

A: Abnormal and unnecessary growth of cells termed cancer. Mutations in DNA causes cancer. In the…

Q: What three molecular mechanisms alter chromatin structure and are responsible for many epigenetic…

A: Step 1-  A gene is the essential physical and useful unit of heredity. Genes are comprised of DNA…

Q: Explain about the epigenetic differences ?

A: Introduction Expression of gene is highly under control by various mechanisms such as histone…

Q: What is the difference between silencing genes by imprintingand silencing by epigenetic…

A: Genomic imprinting is a process of silencing genes by the process of DNA methylation. The…

Q: Can transposons cause cancer?

A: A gene is that the primary physical and useful unit of heredity. "Genes" are created from…

Q: 1. Epigenetic marks refer to modifications to DNA and proteins that in tum regulate gene expression.…

A: Different macromolecules are present in humans. They include carbohydrates, lipids, proteins, and…

Q: CpG is an epigenetic term that means: Select one: a. The binding of cytosine with the following…

A: We know that, DNA is the genetic material of almost all living organisms. It is made up of monomers…

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: Given, X is a cancer cell line which was treated with a drug Y. It resulted in the increase of…

Q: What is the key difference between cis- and trans-epigenetic mechanisms for maintaining an…

A: Epigenetics is the branch of genetics that studies heritable traits that are not influenced by the…

Q: What does a suppressor mutation suppress? What is the differencebetween an intragenic and an…

A: Mutation, an alteration in the genetic material of a cell of a living organism or of a virus that is…

Q: What types of histone modifications are responsible for epigenetic phenotypes?

A: Histones are the set of positively charged proteins. Histones are responsible for providing…

Q: What DNA chemical modification can change the expression level of a target gene without sequence…

A: Introduction Epigenetics refers to the heritable or non-heritable changes in gene expression,…

Q: What are the requirements for normal cell division? What are the requirements for cancer cells…

A: Mutation is defined as an erroneous change within the gene sequence of an organism that leads to a…

Q: According to the multi-hit model, more than one mutation must occur in a cell for cancer to develop.…

A: A new multihit model of carcinogenesis is produced for use in assessing age-explicit disease rate…

Q: Which of the following is not a possible outcome of changing the epigenetic code? a) exposure of…

A: * Epigenetic code is an defining code in eukaryotic cells in which each cell consist specific…

Q: Describe how mutations in genome maintenance factors promote tumorigenesis. Why would inactivation…

A: The cells are basic units of life. When any mutation in the gene takes place due to any radiation or…

Q: Epigenetic changes in gene regulation are caused by ________.     missing nucleotides or chromosomes…

A: Epigenetic  Epigenetic is a reversible change in the DNA which controls the expression of genes.

Q: What are epigenetic changes?

A: Epigenetics refers to the study of heritable changes in gene expression that do not involve changes…

Q: Is RNA silencing an environmentally-induced epigenetic change? Explain.

A: The regulation of gene expression via alterations to DNA, RNA, or histone proteins is known as…

Q: Are mutations good or bad? Explain your response to this question.

A: Any alteration in the sequence of deoxyribonucleic acid (DNA) is called a mutation. It occurs…

Q: How can environmental agents that do not cause gene mutationscontribute to cancer? Would these…

A: A gene is a particular sequence of nucleotides in RNA or DNA that is generally located on a…

Q: Which of the following is NOT a description of an epigenetic modification? -The persistence of gene…

A: ANSWER;-  Regulatory patterns that persist in the absence of the original signal. It is NOT a…

Q: A gene, which we will call gene C, can be epigenetically modified in such a way that its expression…

A: Introduction: Gene is the structural and functional unit of inheritance or heredity which transfers…

Q: What is a signal-transduction pathway? Why are mutations in components of signal-transduction…

A: Cells are the basic structural, functional, and biological units of all living organisms. It is the…

Q: Are all pluripotent stem cells created equal, however?

A: Pluripotent cells are capable of repeated division to form most or all of the cell types but cannot…

Q: What are stem cells, and what safety mechanism protects them from mutation?

A: Stem cell  Stem cells are pluripotent cell that is produced by bone marrow cells.

Q: If p63 can bind to the same promoter elements as p53, why would it be considered an inhibitor of…

A: Promoters are DNA sequences that function as a kind of "On" switch to start the biological process…

Q: Define epigenetics and epigenetic silencing.

A: Introduction :- Epigenetics is the study of how your actions and environment can alter how your…

Q: What type of epigenetic changes are associated with cancer?

A: Epigenetic changes or modifications are important for maintenance of tissue specific gene…

Q: How can this identical set of genetic instructions produce different types of cells?

A: Genes are hereditary components that are located on the chromosomes. They can be passed on from one…

Q: What are enhancers and How do enhancers work?

A: Transcription is defined as the transcribing the DNA sequence into  RNA sequence by using the DNA as…

Q: What is the rationale for synthesizing and rapidly degrading p53 protein in the cell?

A: P53 is a nuclear transcription factor with pro apoptotic function as 50% of human Kansas carries…

Q: DNA sequencing has provided data to indicate that cancer cells may contain tens of thousands of…

A: Cancer cells are defined as the cells that will divide relentlessly and continuously; thus, forming…

Q: Why do mutations in genes that encode DNA-repair enzymes often produce a predisposition to cancer?

A: Cancer is the disease caused by loss of control over the process of cell division.

Q: Can you think of two ways in which the function of p53 can be disrupted?

A: P53 is a tumor suppressor gene which normally restrains growth and mutation in this causes loss of…

Q: How can mutations in noncoding segments of DNA contribute to the development of cancers?

A: The functions segment of hereditary material that mainly codes for the proteins is a gene. The…

Q: What are induced pluripotent stem cells? How are they derived from adult somatic cells?

A: Pluripotent stem cells are those cells that have the ability to renew themselves by dividing and…

Q: Epigenetic changes in gene regulation are caused by _ _ _ _ _ _ _    a. missing nucleotides or…

A: Epigenetics refers to both heritable and non heritable changes in gene expression that are not…