Norflaxacin is a cidal broad spectrum antibiotic that functions by inhibiting DNA gyrase in gram +/- cells. (DNA gyrase reverses supercoiling which occurs when DNA is unwound during replication). Why does Norflaxacin harm infecting bacteria but not human cells?

Norflaxacin is a cidal broad spectrum antibiotic that functions by inhibiting DNA gyrase in gram +/- cells. (DNA gyrase reverses supercoiling which occurs when DNA is unwound during replication). Why does Norflaxacin harm infecting bacteria but not human cells?

Biology Today and Tomorrow without Physiology (MindTap Course List)

5th Edition

ISBN:9781305117396

Author:Cecie Starr, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Christine Evers, Lisa Starr

Chapter10: Biotechnology

Section: Chapter Questions

Problem 1CT

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Concept explainers

Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes encode specific viral proteins.

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