Para-aminobenzoic acid has two ionizable groups. One is a carboxylic acid that ionizes through loss of a proton thereby forming a charged para-aminobenzoic acid carboxylate anion, and the other is an amine connected to an aromatic (benzene) ring that ionizes by accepting an H+ to form a positively charged ammonium ion. The pk of the carboxylic acid is 4.9 and the pk of the amino group is 2.5. Assume that the intracellular pH within a bacterial cell is 7.0. H H O-H pk = 2.5 Which of the following structures correctly depicts how most of the para-aminobenzoic acid is ionized at pH 7? A. B. H + H-N- H C. H H. + H-N- H N- H O-H pK₂ = 4.9 D. X o o O-H
Para-aminobenzoic acid has two ionizable groups. One is a carboxylic acid that ionizes through loss of a proton thereby forming a charged para-aminobenzoic acid carboxylate anion, and the other is an amine connected to an aromatic (benzene) ring that ionizes by accepting an H+ to form a positively charged ammonium ion. The pk of the carboxylic acid is 4.9 and the pk of the amino group is 2.5. Assume that the intracellular pH within a bacterial cell is 7.0. H H O-H pk = 2.5 Which of the following structures correctly depicts how most of the para-aminobenzoic acid is ionized at pH 7? A. B. H + H-N- H C. H H. + H-N- H N- H O-H pK₂ = 4.9 D. X o o O-H
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.SE: Something Extra
Problem 50AP: The -helical parts of myoglobin and other proteins stop whenever a proline residue is encountered in...
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