PLP can catalyze both a,ß-elimination reactions (Problem 33) and B,y-elimination reactions. Propose a mechanism for the following PLP-catalyzedB,y-elimination reaction:enzymeO.+ X + NH4PLP*NH3

Structure of PLP is as follows: In the first step aldehyde group of the coenzyme forms the imine…

Answered: PLP can catalyze both a,ß-elimination…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter19: Enolate Anions And Enamines

Section: Chapter Questions

Problem 19.81P

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PLP can catalyze both a,ß-elimination reactions (Problem 33) and B,y-elimination reactions. Propose a mechanism for the following PLP-catalyzed B,y-elimination reaction: enzyme O. + X + NH4 PLP *NH3