Protein levels and mRNA levels for a particualr gene don’t always match.  For example, the GCN4 gene in yeast is always producing mRNA, but the Gcn4 protein is only made when the cells are starved.What does this mean for diagnostic techniques that try to look at gene expression?

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Asked Dec 1, 2019
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Protein levels and mRNA levels for a particualr gene don’t always match.  For example, the GCN4 gene in yeast is always producing mRNA, but the Gcn4 protein is only made when the cells are starved.

What does this mean for diagnostic techniques that try to look at gene expression?

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Gene expression techniques such as PCR (polymerase chain reaction), microarrays and some assays su...

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