Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter4: Basic Immunology And Immunohematology
Section4.3: Tests For Rheumatoid Factors
Problem 3RQ
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Question
Provide some reasons in vivo tests would not be as reliable as immunoassay
tests.
Expert Solution
Step 1
IMMUNOASSAY test can be used for the presence of specific antibody or specific antigen in the blood or other fluids. When these tests are used for the detection of antibody in the blood, test contain specific antigen as a part of the system.
IN VIVO tests are done in living organism such as laboratory animal or human. Animal testing and clinical trials are major elements of in vivo research.
It is often used to refer experimentation done in live isolated cells rather than in whole organism, example, cultured cells derived from biopsies.
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