QUESTION 2  ‘’Viruses cannot be grown in standard microbiological culture such as broth and agar. They need to be  cultured in the presence of a suitable host such as prokaryotic cells (easiest to grow in the lab), plants  and animals because they are unable to reproduce independently in living cells’’. 2.1 Briefly, describe the advantages and disadvantages of cell culture.  2.2 What are the changes that are brought by a virus to a cell? In your response, make reference to the  cytopathic effect (CPE).

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Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes encode specific viral proteins.