reactant: 0.15g of p-amionphenol (MW=109.1) 0.165 ml of acetic anhyride (mw= 102.1 d= 1.08 ml) product: acetaminophen mw = 151.2 Calculate the E-factor of the process (70% actual yield).

Principles of Instrumental Analysis
7th Edition
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Chapter11: Atomic Mass Spectrometry
Section: Chapter Questions
Problem 11.10QAP
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reactant:

0.15g of p-amionphenol (MW=109.1)

0.165 ml of acetic anhyride (mw= 102.1 d= 1.08 ml)

product:

acetaminophen mw = 151.2

  1. Calculate the E-factor of the process (70% actual yield).
Expert Solution
Step 1

The chemical equation for the reaction between the given reactants is;

Chemistry homework question answer, step 1, image 1

Step 2

The number of moles of p-aminophenol and acetic anhydride are;

np-aminophenol=mp-aminophenolMMp-aminophenol=0.15 g109.1 g/mol=1.375×10-3 molnacetic anhydride=macetic anhydrideMMacetic anhydride=0.165 mL×1.08 g mL-1102.1 g/mol=1.745×10-3 mol

 

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