Question
Asked Mar 21, 2020
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Relate the primary methods of diagnosing, treating, and preventing
allergies.

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Expert Answer

Step 1

Allergy can be defined as an immune-mediated inflammatory response to common environmental allergens such as particular food, pollen, fur, or dust, that are usually harmless. 

Step 2

Diagnosis:

The diagnosis of allergy is dependent on a history of symptoms on exposure to an allergen together with the detection of "allergen-specific immunoglobulin" called IgE. Allergen-specific IgE is detected by skin prick testing and by blood specific IgE testing.

Skin prick testing requires appropriate precautions. A doctor should be present for safety and test analysis and interpretation. Accurate diagnosis of allergies creates therapeutic benefits such as allergen immunotherapy and allergen avoidance. 

Step 3

Treatment:

Allergen-specific immunotherapy involves the administration of increasing doses of allergen to a patient to attain clinical and immunological tolerance over time. Allergen injection immunotherapy induces T cell immuno-tolerance by various methods, including decreased allergen-induced proliferation, alteration of secreted cytokines, stimulation of cell apoptosis, and the generation of T regulatory cells. This results in a reduction in inflammatory cells and ...

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