Remembering that the wobble base of the tRNA is the5′ base of the anticodon:a. In human tRNAs, what are the sequences of allpossible anticodons that were originally transcribedwith A in the wobble position? (Assume this A isalways modified to I.)b. In human tRNAs, what are the sequences of allpossible anticodons that were originally transcribedwith U in the wobble position? (Note: Any singletype of tRNA with a U at the wobble position canbe modified only in a single way.)c. How might the wobble Us in each of the anticodonsin (b) be modified and still be consistent with thegenetic code?d. What is the theoretical minimal number ofdifferent tRNA genes that must exist in thehuman genome? (Assume that xo5U pairs with A,G, or U only.)

Biology Today and Tomorrow without Physiology (MindTap Course List)
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Chapter7: Gene Expression And Control
Section: Chapter Questions
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Remembering that the wobble base of the tRNA is the
5′ base of the anticodon:
a. In human tRNAs, what are the sequences of all
possible anticodons that were originally transcribed
with A in the wobble position? (Assume this A is
always modified to I.)
b. In human tRNAs, what are the sequences of all
possible anticodons that were originally transcribed
with U in the wobble position? (Note: Any single
type of tRNA with a U at the wobble position can
be modified only in a single way.)
c. How might the wobble Us in each of the anticodons
in (b) be modified and still be consistent with the
genetic code?
d. What is the theoretical minimal number of
different tRNA genes that must exist in the
human genome? (Assume that xo5
U pairs with A,
G, or U only.)

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