Show how the acetoacetic ester synthesis can be used to prepare this ketone. Ph 4-Phenyl-2-butanone

Q: Propose preparative routes to the following ketones using an enamine intermediate - you must make…

A: In this question, we have to synthesized the given product a) and b) by using enamine intermediate.…

Q: To prepare the compound below, how many alkylations of an acetoacetic ester as part of the…

A: The acetoacetic ester synthesis allows conversion Of ethyl aceto acetate into methyl ketone with one…

Q: Show how the following compounds can be made using the malonic ester synthesis. ) 4-phenylbutanoic…

A: Malonic ester reacts with phenyl ethyl bromide in presence of sodium ethoxide, From which sodium…

Q: Propose a mechanism for the following reaction:

A: This is a reaction of aldehydes with amines, where amine nitrogen atom attacks the carbonyl carbon,…

Q: Propose a synthesis to convert the shown reactants into the shown products. For the first synthesis,…

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Q: Show how an acetoacetic ester synthesis might be used to form a d@diketone such asheptane-2,6-dione.

A: Reactions in which an ester is alkylated at the alpha position to both carbonyl carbon atoms using a…

Q: How would the acetoacetic ester synthesis to prepare the following? You use

A: Acetoacetic esters are mainly used to make C-C bond via enolate chemistry.

Q: Propose a synthesis of the tranquilizer valnoctamide from diethyl malonate.

A: Synthesis of tranquilizer valnoctamide: In this synthesis, the first step involves diethyl malonate…

Q: The indicated ester can undergo hydrolysis by either a chemical or an enzymatic process. Show the…

A: In the above reaction, ester Hydrolysis takes place. One base catalysis  chemically and one is…

Q: Predict the products of aldol condensation, followed by dehydration, of the followingketones and…

A: (c) The products of aldol condensation, followed by dehydration of the cyclohexanone is shown below,

Q: Show how the p-chloroaniline acid can be synthesized from benzene:

A: p-chloroaniline- Molecular formula of p-chloroaniline is C6H6 Melting point of p-chloroaniline is…

Q: Propose a mechanism for the acid-catalyzed hydrolysis of cyclohexanone dimethyl acetal.

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Q: A variation of the acetamidomalonate synthesis can be used to synthesize threonine. The process…

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Q: Show how you would synthesize the following esters from appropriate acyl chloridesand alcohols.(a)…

A: Since your question has multiple sub-parts, we are solving only first three sub-parts for you. If…

Q: Show how to synthesize the following compound  using either the malonic ester synthesis or the…

A: Synthesis of product using various reagents helps in the generation of a new structure.

Q: Specify whether the ketones below can be prepared by acetoacetic ester synthesis.

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Q: Derive a method for the preparation of the following compounds using acetoacetic ester or malonic…

A: Detail synthetic pathway is given below

Q: The ketone whose 1H NMR spectrum is shown here was obtained as the product of an acetoacetic ester…

A: The structure of the ketone can be predicted from its 1H-NMR spectrum. There are five signals…

Q: Predict the products of aldol condensation, followed by dehydration, of the followingketones and…

A: (a)

Q: Show how the acetoacetic ester synthesis is used to make 3-propylhex-5-en-2-one.S

A:

Q: How would you prepare the following ketones using an acetoacetic ester synthesis?

A: Acetoacetic ester synthesis involves the formation of alpha substituted acetone.

Q: Show how you would use an acid chloride as an intermediate to synthesize) phenyl propionate…

A: The use of an acid chloride as an intermediate to synthesize phenyl propionate from propionic acid…

Q: 1. Show how to synthesis the following compounds using either a malonic ester synthesis or an…

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Q: He OH et worle HO

A: An acetal is a compound that has two ether-like -OR groups bonded to the same carbon atom of what…

Q: Using cyclopentanone as the reactant, show the product of a. acid-catalyzed keto–enol…

A: The acid-catalyzed keto-enol interconvertion has to be given.

Q: Show how the acetoacetic ester synthesis can be used to prepare the compound

A: Retrosynthesis

Q: Show how the malonic ester synthesis can be used to prepare 3-phenylpropanoic acid.

A:

Q: Show how to synthesize the following compound  using either the malonic ester synthesis or the…

A: We can use the malonic ester synthesis pathway to get Cyclobutyl methyl ketone. The synthesis…

Q: Propose a mechanism for conversion of the dianion to the ketone under mildly acidic conditions.

A:

Q: Propose a mechanism for the acid-catalyzed reaction of benzaldehyde with methanol to give…

A: The addition of an alcohol functional group to carbonyl compounds such as aldehydes and ketones…

Q: Show how to synthesize the following compound  using either the malonic ester synthesis or the…

A: Acetoacetic ester synthesis is a chemical reaction where ethyl acetoacetate is alkylated at the…

Q: Propose an efficient synthesis of the following compound using the malonic ester synthesis. Propose…

A: 1. Reaction with mechanism of synthesis

Q: What is the reaction mechanism? (Esterification) Please Explain also. Starting Materials:…

A: In the esterification reaction, the carboxylic acid reacts with alcohol in presence of an acid to…

Q: Show how the malonic ester synthesis can be used to prepare the following substituted acetic acid

A: Given compound,

Q: Propose a synthesis for each ketone, using as one step in the sequence a Claisen condensation and…

A:

Q: Show how to synthesize the following compound  using either the malonic ester synthesis or the…

A: The malonic ester synthesis of 2-Propyl-1,3-propanediol undergoes a nuclophilic attack using strong…

Q: Draw the mechanism for the reaction of benzyl nitrile with methyl Grignard followed by an acid…

A: Nucleophilic addition reaction followed by acid base reaction gives the hydrolysis product.

Q: Show how the following compounds can be made using the malonic ester synthesis. ) 2-methylpropanoic…

A: Given:   The given compound is 2-methylpropanoic acid.

Q: Propose a mechanism for the formation of methyl benzoate when ethyl benzoate is heated in methanol…

A: Here we are required to provide the mechanism of formation of methyl benzoate

Q: Predict the products of aldol condensation, followed by dehydration, of the followingketones and…

A: a) The first step in aldol condensation reaction is the formation of enolate ion by the abstraction…

Q: Show how the following compounds can be made using the malonic ester synthesis.(a) 3-phenylpropanoic…

A: Malonic ester for acid synthesis :  Malonic ester is a good reagent which can be used for the…

Q: How would you use the aceroacetic ester synthesis to prepare the following?

A: Enolates reacts via SN2 fashion to give alkylation product.

Q: Show experimental conditions by which to carry out the following synthesis. MeOOC Ph CHO + OMe Ph…

A: The experimental conditions by which the given synthesis occurs has to be given.

Q: Show how each transformation may be accomplished by using a nitrile as an intermediate. You may use…

A: (a)

Q: Show how the malonic ester synthesis can be used to prepare carboxylic acid A. (Given: the structure…

A: