СHз HЭС—N. lbogaine Cocaine

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
Problem 3CRQ
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Below find the structures for ibogaine and cocaine.

Ibogaine and cocaine inhibit the dopamine active transporter (DAT).  This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase.  Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively.

(a) Define secondary active transport.

(b) Is ibogaine an effective treatment for cocaine based on DAT binding?

СHз
HЭС—N.
lbogaine
Cocaine
Transcribed Image Text:СHз HЭС—N. lbogaine Cocaine
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