Asked Nov 14, 2019

Below find the structures for ibogaine and cocaine.

Ibogaine and cocaine inhibit the dopamine active transporter (DAT).  This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase.  Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively.

(a) Define secondary active transport.

(b) Is ibogaine an effective treatment for cocaine based on DAT binding?


Image Transcriptionclose

СHз HЭС—N. lbogaine Cocaine


Expert Answer

Step 1

A secondary active transport couples the uphill (against the concentration gradient) transport of a molecule to the downhill (along the concentration gradient) transport of another molecule. It does n...

Want to see the full answer?

See Solution

Check out a sample Q&A here.

Want to see this answer and more?

Solutions are written by subject experts who are available 24/7. Questions are typically answered within 1 hour.*

See Solution
*Response times may vary by subject and question.
Tagged in



Related Biology Q&A

Find answers to questions asked by student like you

Show more Q&A add

Q: Crossing-over

A: As per our honor code we are authorized to answer only one question at a moment. In case you need ou...


Q: which of these could lead to the mistake evident in the karyotype? A) a failure of cytokinesis after...

A: The Correct answer is A, B, and D.A karyotype is a pictorial representation of the chromosomal const...


Q: Is their a correlation between age and allergic reaction?

A: Allergy is the immune response for particular substances like pollen, dust, fur and some food partic...


Q: What is the differece between disinfection and sterilization? What is the dfference between bacteria...

A: Disinfection and sterilization are essential for ensuring that medical and surgical instruments do n...


Q: Living things respond to the environment, grow, and maintain homeostasis.  Explain how this ability ...

A: All living organisms sense and respond to the change, making adjustments that keep internal environm...


Q: Name the muscle functions.

A: Muscle is a soft tissue found in animals and humans. It is composed of actin and myosin protein fila...


Q: What space within bone does an osteocytes occupy?

A: BoneBone is a connective tissue that exhibits four types of cells: osteoblasts, bone lining cells, o...


Q: How would a change in the temperature at which something was incubated affect the amount of mold gro...

A: The differential growth patterns of organisms are due to the temperature sensitivity of the enzymes....


Q: Define wave summation, unfused and fused tetanus

A: The contraction of skeletal muscle is affected by the frequency at which action potential is fired b...