ȘO, Na* SO, Na SO, Nat SO, Na* SO, Na*

Q: ОН S. NH2 HO NH2 Thyrosine (tyr) Methionine (met)

A: Zwitter ion- it is as ion possessing both positive and negative electrical charges.

Q: What is the pl for the polypeptide ALRHEN? Use pka of 8 for the N-terminus and 4 for the C-terminus.

A: pI is defined as the the pH of the solution at which the amino acid is present at iso-electronic…

Q: Given pKa values for ionizable groups from Table 27.2, sketch curves for the titration of Q.)…

A:

Q: Angiotensin II is a polypeptide that regulates blood pressure. 2nd attempt Enter the amino acids, in…

A:

Q: Calculate the pI value of GE- dipeptide   The pKa values of the terminal amino and carboxyl groups…

A: Calculate the pI value of GE- dipeptide ?

Q: Which amino acid listed in the pKa table may behave as a zwitterion at a pH of 7.0-7.4?

A: An amino acid acts as a zwitterion at its isoelectric point.

Q: What is the isoelectric point for the peptide GHIKL at pH 6? Draw the titration curve, showing pI,…

A: The mentioned peptide is GHIKL.

Q: the same 10.00 mL of a 0.5 M NaOH is added to 150.0 mL of MOPS buffer. The buffer contains 0.500M…

A:

Q: Draw the structure of the following molecule The amino acid lysine at pH 12

A: At pH > 10.5 , Lysine remains in deprotonated state.

Q: At very low pH, alanine is a diprotic acid that can be represented as H3N1-CH(CH3)-COOH. The pKa of…

A: A diprotic acid contains two types of acidic groups. The amino acid contains these two groups: 1.…

Q: 8) A neutral amino acid with a pKa: of 4.56 and a pKa2 of 8.30 is dissolved in a solution with a pH…

A:

Q: Explain why the pKa of the ‒ NH3+ group of an α-amino acid is lower than the pKa of the ammonium ion…

A: In α-amino acid, due to the presence of the electron withdrawing carboxyl group the electron density…

Q: What is the amino terminal residue? What is the carboxyl terminal residue? How many amino acid…

A: as per the policy guidelines we are here to solve first three questions only. amino acids are the…

Q: For the following peptide chain WHD (Tryptophan-Histidine-Aspartic acid) :   pH = 8 Given pKa value…

A: If the pKa of acid is lower than the pH of the solution then the proton will remain intact and will…

Q: A professor was preparing a manuscript for publication in which she reported that the pI of the…

A: The average of the similarly ionizing groups is the Pl of most of the amino acids that have an…

Q: The isoelectric point, pl, of the protein deoxyribonuclease I is 10.2, while that of clostripain is…

A: •Firstly understand about ISOELECTRIC POINT:-Isoelectric point is that value of pH where a molecule…

Q: Use these pka values to calculate the charge on the peptide below at pH 6. alpha COOH 2.0 side Chain…

A: T: Threonine, pKa: 9.0 S: Serine Y: Tyrosine, pKa: 10.0 M: Methionine C: Cysteine, pKa: 8.0 F:…

Q: a. Look at the non-natural amino acid below and note that the pka's of particular groups are…

A: As per our company guidelines we are supposed to answer first 3 sub-parts. Kindly repost the other…

Q: What is the net charge on the tripeptide His-Glu-Lys at pH 7? The table below gives the pKa's of the…

A: Apart from the main -NH2 and -COOH groups, histidine has a side group (imidazole ring) with pKa =…

Q: Explain why the pKa of the - NH3+ group of an a-amino acid is lower than the pKa of the ammonium ion…

A: In primary (1o) amine, RNH3+, the -NH3+ group is attached to the electron-donating group that is…

Q: Explain the order of elution (with a buffer of pH 4) of the following pairs of amino acids through a…

A: (a)  Comparing the structure of aspartate and serine as shown. Aspartate has the carbonyl group…

Q: 2. Please identify the following amino acid then calculate for pl. H2N OH NH2 RKa of carboxyl group:…

A: Given amino acid is Lysine.

Q: A chromatogram showing the results for an amino acid test show a solvent line of 7.5cm. If the amino…

A:

Q: Draw the structure for the peptide CF. • You do not have to consider stereochemistry. • You do not…

A: Given peptide, CF C- Cysteine F - Phenylalanine

Q: . The pKa of the carboxylic acid group is 2.36. The pKa of the amino group is 9.76. Show how to…

A: Isoelectronic point is the PH at which maximum concentration of zwitter ion exist. That means a…

Q: Give the numbers of peptide bond present in given structure, structure is given at pH 10.5,  find…

A: The CO- NH bond is called peptide bond. A peptide bond connects two Amino acid units. Amino acid…

Q: His-Met-Asp-Tyr-Phe-Ser Calculate an approximate pI (isoelectric point) for this peptide.

A: The isoelectric point (pI) is defined as that pH of aqueous solution of amino acids where the…

Q: The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COOH…

A:

Q: Draw a formula for Thr-Ala-Ala (T-A-A) in its predominant ionic form at pH 7.3. You may assume for…

A: Here we are required to draw the structure of peptide predominant at pH 7.3

Q: An amino acid's guadinine side chain has a pKa of 12.5 what is the ratio of uncharged to charged…

A: An amino acid's guanidine side chain has a pKa of 12.5. The ratio of uncharged to charged guanidine…

Q: What is the K, of the amino acid leucine if it is 34.5% disso- ciated at pH = 9.46? |3D

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Please consider the structural formula of the amino acid shown below when answering the following…

A: (A) draw the form of this amino acid that predominates at pH 8  This pH is highly basic so that both…

Q: ine is a diprotic amino acid with a pk = 2.344 for the carboxylic group and a pK, = 9.868 for the…

A:

Q: The pKa values of an amino acid are the following: pK1 = 2.18;  pK2 = 8.95;  pK3 = 10.53, what is…

A: Tha pKa values indicates ;  pK1 = 2.18 ( this is the pKa of acidic group)  pK2 and pK3 are the pKa…

Q: Mark the TRUE alternative for the following peptide: a) For a pH of 7.0 this peptide will migrate…

A: For an ionizable group on a peptide, if pH < pKa, the group remains protonated, and if pH >…

Q: Glycine solution was titrated against NaOH and pH of the final solution was 4.8. Given that the pKa¹…

A: Given data :  Glycine solution was titrated against NaOH and pH of the final solution was 4.8.…

Q: An amino acid residue side chain is deprontonated at pH9.5. What is the pKa of this residue if it is…

A: an animo acid is a biomolecule which as both basic amine group and acidic group ( carboxylic acid)…

Q: Chemistry Given TETRAPEPTIDE: Prolinyl-Argininyl-Cysteinyl-Tryptophan Predict the direction of the…

A: The given peptide according to the given sequence is: Proline makes the N terminal of the peptide.…

Q: Dutline the steps used to find values for a BLOSUM amino acid similarity matrix.

A:

Q: Calculate the pI of this peptide. Calculate the net charge of this peptide at pH 2, pH 7, and pH 11.

A:

Q: Draw a structural formula for the form of   amino acid most prevalent at pH 1.0. (a) Arginine

A: Amino acids contain an amino group and a carboxyl group at the same carbon with a side chain (-R)…

Q: Arginine has ionizable groups with pKa values of 2.17 9.04, and 12.48. A researcher makes up 73 mL…

A: The question is based on the concept of PH.  It involves calculation for amino acid Arginine. we…

Q: Rank the migration rate of the following amino acids in ascending order towards  the cathode when…

A: PI stands for isoelectric point. If pH is less than isoelectric point then amino acid will move…

Q: Calculate the percentage ionization (i.e. [base]/[acid]x100) in these amino acid side chains at the…

A: Since you have posted a question with multiple sub-parts, we will solve first three subpartsfor you.…

Q: The amino acid histidine has a side chain for which the pKa 6.0. Calculate what fraction of the…

A: from Henderson Hasselbach equation we have pH = pka + log [conjugate base] /[ acid form] acid form…

Q: The pKa values for Lysine are 1.92/ 9.99/13.8. At what pH will the amino acid not migrate in an…

A: We have given  the pKa values for lysine as follows 1.92, 9.99, and 13.8. and ask to find at what pH…

Q: Alanine is a diprotic amino acid with a pk, = 2.344 for the carboxylic group and a pka = 9.868 for…

A: Ajj

Q: The pKa for the side chain amino group in lysine is 10.4. If we were working at physiological pH…

A: At pH below the pKa for the amino acid is  protonated and at  pH above the pKa then it is…

Spectroanalytical Methods

Spectroanalytical methods measure the wavelength and intensity of radiations that are either emitted or absorbed by a molecular or atomic species. These methods are useful for evaluating the electronic or atomic arrangement of the molecules of a given analyte.