some eukaryotic mRNAs have internal ribosome binding sites, where ribosomes can bind without first attaching to the 5′ cap. Yet all eukaryotic mRNAs are capped, and cap-dependent translation is highly efficient. What might be the advantage of having internal ribosome binding sites if the cap permits the initiation of translation and all eukaryotic mRNAs are capped?

Question

some eukaryotic mRNAs have internal
ribosome binding sites, where ribosomes can bind without first
attaching to the 5′ cap. Yet all eukaryotic mRNAs are capped, and
cap-dependent translation is highly efficient. What might be the
advantage of having internal ribosome binding sites if the cap permits
the initiation of translation and all eukaryotic mRNAs are capped?

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