The amino acid sequence of part of a protein has beendetermined:N . . . Gly Ala Pro Arg Lys . . . CA mutation has been induced in the gene encodingthis protein using the mutagen proflavin. The resultingutant protein can be purified and its amino acidsequence determined. The amino acid sequence of themutant protein is exactly the same as the amino acidsequence of the wild-type protein from the N terminus of the protein to the glycine in the preceding sequence. Starting with this glycine, the sequence ofamino acids is changed to the following:N . . . Gly His Gln Gly Lys . . . CUsing the amino acid sequences, one can determinethe sequence of 14 nucleotides from the wild-typegene encoding this protein. What is this sequence?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 18QP: The following is a portion of a protein: met-trp-tyr-arg-gly-pro-thr-Various mutant forms of this...
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The amino acid sequence of part of a protein has been
determined:
N . . . Gly Ala Pro Arg Lys . . . C
A mutation has been induced in the gene encoding
this protein using the mutagen proflavin. The resultingutant protein can be purified and its amino acid
sequence determined. The amino acid sequence of the
mutant protein is exactly the same as the amino acid
sequence of the wild-type protein from the N terminus of the protein to the glycine in the preceding sequence. Starting with this glycine, the sequence of
amino acids is changed to the following:
N . . . Gly His Gln Gly Lys . . . C
Using the amino acid sequences, one can determine
the sequence of 14 nucleotides from the wild-type
gene encoding this protein. What is this sequence?

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