The figure below shows amino acid interactions between the a /B2 subunit interface of hemoglobin. These interactions stabilize the T state of the protein. Based on the figure below, which amino acid in the picture below, if replaced with glutamate, would decrease the Ka of hemoglobin for O2 the most? Include both the residue and the residue number in your response (For example, V1 or K127). to B, V34 8- a, R141 D126 K127 Noncovalent

Human Heredity: Principles and Issues (MindTap Course List)
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Author:Michael Cummings
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Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 19QP: A person was found to have very low levels of functional beta globin mRNA and therefore very low...
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The figure below shows amino acid interactions between the a /B2 subunit interface of hemoglobin.
These interactions stabilize the T state of the protein. Based on the figure below, which amino acid in
the picture below, if replaced with glutamate, would decrease the Ka of hemoglobin for O2 the most?
Include both the residue and the residue number in your response (For example, V1 or K127).
to
B, V34
8-
a, R141
D126
K127
Noncovalent
Transcribed Image Text:The figure below shows amino acid interactions between the a /B2 subunit interface of hemoglobin. These interactions stabilize the T state of the protein. Based on the figure below, which amino acid in the picture below, if replaced with glutamate, would decrease the Ka of hemoglobin for O2 the most? Include both the residue and the residue number in your response (For example, V1 or K127). to B, V34 8- a, R141 D126 K127 Noncovalent
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