The following is a list of mutational changes. For eachof the specific mutations described, indicate which ofthe terms in the right-hand column applies, either as adescription of the mutation or as a possible cause.More than one term from the right column can applyto each statement in the left column.1. an A–T base pair in the wild-type gene ischanged to a G–C pair2. an A–T base pair is changed to a T–A pair3. the sequence AAGCTTATCG is changed toAAGCTATCG4. the sequence CAGCAGCAGCAGCAGCAGis changed toCAGCAGCAGCAGCAGCAGCAGCAG5. the sequence AACGTTATCG is changed toAATGTTATCG6. the sequence AACGTCACACACACATCGis changed to AACGTCACATCG7. the sequence AAGCTTATCG is changed toAAGCTTTATCGa. transitionb. basesubstitutionc. transversiond. deletione. insertionf. deaminationg. X-rayirradiationh. intercalatori. slippedmispairing

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 9QP: Define and compare the following types of nucleotide substitutions. Which is likely to cause the...
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The following is a list of mutational changes. For each
of the specific mutations described, indicate which of
the terms in the right-hand column applies, either as a
description of the mutation or as a possible cause.
More than one term from the right column can apply
to each statement in the left column.
1. an A–T base pair in the wild-type gene is
changed to a G–C pair
2. an A–T base pair is changed to a T–A pair
3. the sequence AAGCTTATCG is changed to
AAGCTATCG
4. the sequence CAGCAGCAGCAGCAGCAG
is changed to
CAGCAGCAGCAGCAGCAGCAGCAG
5. the sequence AACGTTATCG is changed to
AATGTTATCG
6. the sequence AACGTCACACACACATCG
is changed to AACGTCACATCG
7. the sequence AAGCTTATCG is changed to
AAGCTTTATCG
a. transition
b. base
substitution
c. transversion
d. deletion
e. insertion
f. deamination
g. X-ray
irradiation
h. intercalator
i. slipped
mispairing

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