The gene that determines ABO blood type and the gene that is mutated in Nail- Patella syndrome (NPS) are both located on chromosome 19 in humans. Nail-patella syndrome is dominant and completely penetrant. A B O AB B A A AB A O B 0 O A O AB B ABA a. From the pedigree of the family shown above, determine whether the gene determining ABO blood typ is linked to the NPS gene and, if so, calculate the map distance. Show your work b. The woman (indicated with an arrow) marries to a man with blood type B. Their first child is a boy of blood type O who is unaffected by NPS. What is the probability that their second child will be an unaffected girl with type B blood?
The gene that determines ABO blood type and the gene that is mutated in Nail- Patella syndrome (NPS) are both located on chromosome 19 in humans. Nail-patella syndrome is dominant and completely penetrant. A B O AB B A A AB A O B 0 O A O AB B ABA a. From the pedigree of the family shown above, determine whether the gene determining ABO blood typ is linked to the NPS gene and, if so, calculate the map distance. Show your work b. The woman (indicated with an arrow) marries to a man with blood type B. Their first child is a boy of blood type O who is unaffected by NPS. What is the probability that their second child will be an unaffected girl with type B blood?
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...
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