Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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Show that these results are consistent with the structure of piperidine

The procedure of methylation of amines and thermal decomposition of
quaternary ammonium hydroxides was first reported by Hofmann in 1851, but
its value as a means of structure determination was not appreciated until 1881,
when he published a report of its use to determine the structure of piperidine.
Following are the results obtained by Hofmann.
1. CHI (excess), К,СО,
2. Ag,O, H,O
3. heat
4. CH3I (excess), K,CO3
5. Ag.O, H,О
6. heat
C5H1|N
C;H15N
CH2=CHCH,CH=CH2
Piperidine
(A)
1,4-Pentadiene
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Transcribed Image Text:The procedure of methylation of amines and thermal decomposition of quaternary ammonium hydroxides was first reported by Hofmann in 1851, but its value as a means of structure determination was not appreciated until 1881, when he published a report of its use to determine the structure of piperidine. Following are the results obtained by Hofmann. 1. CHI (excess), К,СО, 2. Ag,O, H,O 3. heat 4. CH3I (excess), K,CO3 5. Ag.O, H,О 6. heat C5H1|N C;H15N CH2=CHCH,CH=CH2 Piperidine (A) 1,4-Pentadiene
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