The separate enantiomers. of 2-hydroxyheptanoic acid were needed for determination of the absolute configuration of verticilide, a potential insecticide. Suggest a possible synthetic route to enantiopure 2-hydroxyheptanoic acid, starting from (R)- or (S)-malic acid. (Please provide details showing the synthetic route.)

The separate enantiomers. of 2-hydroxyheptanoic acid were needed for determination of the absolute configuration of verticilide, a potential insecticide. Suggest a possible synthetic route to enantiopure 2-hydroxyheptanoic acid, starting from (R)- or (S)-malic acid. (Please provide details showing the synthetic route.)

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section: Chapter Questions

Problem 23.37P

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