Type 1 albinism in humans is a rare hereditary condition associated with a reduced amount of active tyrosinase, an enzyme required for the conversion of the amino acid tyrosine to the dark pigment melanin. In the pedigree above, males are indicated by squares, females by circles and individuals with type 1 albinism are indicated by shading. Use A and a for the dominant (sufficient active tyrosinase) and recessive alleles (absent or insufficient tyrosinase activity), respectively. Remember that, when genotype is not known for a dominant phenotype, an m-dash is used (A– = AA or Aa). If individuals B and E marry, what is the probability that their first child will be affected by type 1 albinism? А. 1/2 В. 1/12 С. 1/4 D. 2/3 O E. 1/24
Type 1 albinism in humans is a rare hereditary condition associated with a reduced amount of active tyrosinase, an enzyme required for the conversion of the amino acid tyrosine to the dark pigment melanin. In the pedigree above, males are indicated by squares, females by circles and individuals with type 1 albinism are indicated by shading. Use A and a for the dominant (sufficient active tyrosinase) and recessive alleles (absent or insufficient tyrosinase activity), respectively. Remember that, when genotype is not known for a dominant phenotype, an m-dash is used (A– = AA or Aa). If individuals B and E marry, what is the probability that their first child will be affected by type 1 albinism? А. 1/2 В. 1/12 С. 1/4 D. 2/3 O E. 1/24
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...
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