Use the EGF Pathway passage to answer the questions. EGF signals by binding to cell surface EGF receptors. Which of these observations, if true, would BEST explain EGF's mechanism of action? A. EGF is hydrophilic and can easily diffuse through the cell membrane. B. EGF is hydrophobic and can easily diffuse through the cell membrane. C. EGF is hydrophilic and cannot diffuse through the cell membrane. D. EGF is hydrophobic and cannot diffuse through the cell membrane.
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- A mutation in HER2 that causes receptor dimerization in the absence of signaling molecules. Would cause? Why? A. Decreased proliferation B. Increases proliferationDescribe the concept of a stress activated signaling pathway using an example from the lectures. Explain the role of sensors, transduction pathways, transcription factors and cis-Elements.EGF signals by binding to cell surface EGF receptors. Which of these observations, if true, would BEST explain EGF’s mechanism of action? A. EGF is hydrophilic and can easily diffuse through the cell membrane B. EGF is hydrophobic and can easily diffuse through the cell membrane C. EGF is hydrophilic and cannot diffuse through the cell membrane D. EGF is hydrophobic and cannot diffuse through the cell membrane
- Which describes a cellular role of RanGEF? maintain Ran in the GTP bound form in the nucleus interact with importin-alpha stimulate/facilitate the inactivity of RAN provide the energy for the entry of the importins into the nucleusThis pertains to membrane transport and cell signaling. Give an example in animals and in plants where the two signaling and responding cells are in direct contact.Why are steroids able to diffuse across the plasma membrane? a. Their transport protein moves them through the membrane. b. They are amphipathic, allowing them to interact with the entire phospholipid. c. Cells express channels that let hormones flow down their concentration gradient into the cells. d. They are non-polar molecules.
- Where do DAG and IP3 originate? a. They are formed by phosphorylation of cAMP. b. They are ligands expressed by signaling cells. c. They are hormones that diffuse through the plasma membrane to stimulate protein production. d. They are the cleavage products of the inositol phospholipid, PIP2.Give typing answer with explanation and conclusion Which molecule performs the primary signal transduction step in cell signaling? Choose one: extracellular signal molecule, intracellular protein kinase, receptor protein, transcription regulator, scaffold proteinWhich of these processes is MOST directly involved in the resorption of a tadpole’s tail during development? A. apoptosis B. mitosis C. phagocytosis D. protein synthesis
- What would be the likely result of a mutation of the bcl-2 gene on the level of apoptosis? a. No change b. A decrease in apoptosis c. An increase in apoptosis d. An initial decrease, followed by an increase in apoptosisUse the EGF Pathway passage to answer the questions. Part A Which of these structures, if present in a prokaryote, would prevent the organism from using this type of actin polymerization to chemotax toward a signal? A. cell wall B. flagellum C. mitochondrion D. ribosome Part B In the model proposed, which of these events MOST likely occurs to facilitate chemotaxis? A. Integrins anchor the cell to extracellular components. B. Motor proteins move actin toward the leading edge. C. Mitochondria migrate away from the leading edge. D. Desmosomes anchor the cell to other cells. Part C Based on the researcher’s observations on filamentous actin, what other observation regarding cell chemotaxis was MOST likely observed? A. The cell moved toward the source of the signaling molecule only after the addition of Compound A. B. The cell moved away from the source of the signaling molecule only after the addition of Compound A.…Explain the three stages of cell signaling. a. receptor b. transduction c. response. Attach images