Using effect sizes in Table 1, calculate the polygenic score for Pat and Sal. Their genotypes are show below:Pat: ne/ne Pk/pk Or6/Or6 Dn/dn Or3/Or3Sal: Ne/ne pk/pk Or6/Or6 dn/dn or3/or3People in the US eat more fruit than people in Australia. The GWAS identifies some genes underlying fruit consumption.Which of the below are reasons we can't conclude that Australians are genetically inclined to eat less fruit (pick all that arecorrect)?The genetic basis of fruit consumption may differ between Australia and the USDifferences between the US and Australia may be environmentalThese loci are not in Hardy-Weinberg proportions in AustraliaThe identified loci may not be causal for fruit consumptionThe heritability of fruit consumption in the US is likely zero. - log₁0 (P)52-44-35-19-10-• NEGR1PKHD1OR6B1SNPNEGR1 Ne/nePKHD1 Pk/pkOR6B1 Or6/or6 +0.7DNAJC1 Dn/dn+0.1OR10G3 Or3/or3 -0.3DNAJC1+0.2-0.1chromosome10 11 12OR10G3¡Figure 1: Shown are the genome-wide association results for fresh fruit consumption in alarge sample of Americans. The dotted horizontal line is the genome-wide significance cutoff.13 14 15 16 17 18 19 20 21 22 23Alleles Effect size Table 1: Effect size (in servings) onfruit consumption per day of alleles atthe loci labelled in Fig. 1. Effect sizesrefer to the first (capital letter) allele;lower case alleles have a value of 0.

Name: Using effect sizes in Table 1, calculate the polygenic score for Pat
Uploaded: 2024-03-20T06:43:04.000Z
Channel: Bartleby
Description: Using effect sizes in Table 1, calculate the polygenic score for Pat and Sal. Their genotypes are show below:Pat: ne/ne Pk/pk Or6/Or6 Dn/dn Or3/Or3Sal: Ne/ne pk/pk Or6/Or6 dn/dn or3/or3People in the US eat more fruit than people in Australia. The GW