Using the data in the first and third columns of the table below, determine the type of inhibition that ibuprofen exerts on prostaglandin endoperoxide synthase and explain why.

Case Studies In Health Information Management
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Chapter3: Informatics, Analytics, And Data use
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Problem 3.34.4C
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Ibuprofen is an inhibitor of prostaglandin endoperoxide synthase. By inhibiting the synthesis of prostaglandins, ibuprofen reduces inflammation and pain. Using the data in the first and third columns of the table below, determine the type of inhibition that ibuprofen exerts on prostaglandin endoperoxide synthase and explain why.

[Arachidonic Rate of formation
acid]
(тм)
Rate of formation
of PGG2 with 10
mg/mL ibuprofen
(тм/min)
of PGG2
(тм/min)
0.5
23.5
16.67
1.0
32.2
25.25
1.5
36.9
30.49
2.5
41.8
37.04
3.5
44.0
38.91
Transcribed Image Text:[Arachidonic Rate of formation acid] (тм) Rate of formation of PGG2 with 10 mg/mL ibuprofen (тм/min) of PGG2 (тм/min) 0.5 23.5 16.67 1.0 32.2 25.25 1.5 36.9 30.49 2.5 41.8 37.04 3.5 44.0 38.91
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