Question
Asked Oct 22, 2019

What are SNARE proteins? What is their role in synaptic vesicle fusion?

check_circleExpert Solution
Step 1

SNARE proteins are protein complexes in yeast and in mammalian cells. The major function of SNARE protein is to mediate the vesicle fusion. That means the fusion of vesicle with their specific target (membrane bound compartments), like lysosome.

Step 2

SNARE proteins are of two types:

  • Vesicle or v-SNAREs: They are incorporated into membranes of transport vesicles at the time of budding.
  • Target or t-SNAREs: They are associated with the nerve terminal membranes.
Step 3

Role of SNAREs in synaptic vesicle fusion:

SNARE complex is formed by the four alpha helices including synaptobrevin, synaptotagmin, syntaxin, and SNAP-25. They serve as calcium sensor and regulates the SNARE zipping. SNARE helps in triggering the release of calcium ions.

In the process of synaptic vesicle...

Want to see the full answer?

See Solution

Check out a sample Q&A here.

Want to see this answer and more?

Solutions are written by subject experts who are available 24/7. Questions are typically answered within 1 hour*

See Solution
*Response times may vary by subject and question
Tagged in

Science

Biology

Related Biology Q&A

Find answers to questions asked by student like you

Show more Q&A add
question_answer

Q: QUESTION 13 Feather color in a certain species of bird is controlled by a pair of alleles that exhib...

A: Hello. Since you have posted multiple questions and not specified which question needs to be solved,...

question_answer

Q: Different strains of Streptococcus pyogenes have different virulence factors, giving these microbes ...

A: Streptococcus pyogenes is the leading cause of uncomplicated bacterial pharyngitis and tonsillitis c...

question_answer

Q: How does spontaneous mutation occur and how is this different from induced mutation?

A: A spontaneous mutation occurs as a result of error in DNA (deoxyribonucleic acid) replication proces...

question_answer

Q: How does meiosis explain the first law of Mendel?

A: The process in which the single cell divides twice in order to produce four cells consisting half th...

question_answer

Q: 7a

A: 7.a Circumduction is the circular movement of a body part. It consists of a combination of flexion, ...

question_answer

Q: Humoral immunity is the part of the adaptive immune system involving: A.cytotoxic T cells killing in...

A: The adaptive immune system is also known as acquired or specific immune system. It is a subset of ov...

question_answer

Q: Answer these questions concerning promoters. a) What role do promoters play in transcription? b) Wha...

A: A region in DNA molecule that initiates transcription of a particular gene is referred to as a promo...

question_answer

Q: How do we know that membrane phospholipids regularly intermingle and move laterally, but rarely flip...

A: The cell membrane is also known as a cytoplasmic membrane or plasma membrane or plasmalemma. S.J.Sin...

question_answer

Q: Why does DNA appear when you add cold alcohol to the strawberry DNA solution?

A: Click to see the answer