What are the consequences of inhibiting the m-phase promoting complex

Q: What inhibit CDK activity by bindingdirectly to the cyclin-CDK complex.

A: A cyclin-dependent kinase complex or CDKC or cyclin-CDK is formed by the interaction of a regulatory…

Q: Phorbol esters have been observed to induce the transcription of AP-1–influenced genes. Explain how…

A: Signal transduction is a process in which signals from the extracellular level enter the…

Q: Describe the function of these molecules that help control the cell cycle A.) M-phase promoting…

A: A) Maturation promoting factor is a cell cycle gatekeeper that controls a cell's transition from the…

Q: Compare and contrast the regulation of Ras with trimeric G proteins

A: Given: Need to compare and contrast the difference between Ras protein with trimeric G protein.

Q: Which of these proteins contain IDRS, and how do the IDRS impact signaling?

A: Intrinsically disordered proteins and region ( IDPs and IDRs) are of crucial importance to cell…

Q: are positive regulators (activators) and negative regulators (repressors)?

A: Gene regulators are divided into two categories: activators and repressors, with activators…

Q: Why doesn't Cdk1 active immediately upon binding to cyclin B? What other components of the cell’s…

A: It includes cell division, replication and growth. All these processes should be carried out in a…

Q: Which compound is a cyclin - dependent kinase inhibitor?

A: Cyclin-dependent kinase inhibitors Cyclin-dependent kinases (CDK) are enzymes involved in cell…

Q: Expression of S-phase genes is activated when P16 inactive or absent P16 active Cdk4 inactive

A: The cell cycle is regulated by cyclins(regulatory proteins present in varying concentrations during…

Q: in a fat cell what is the result of activation of genes by PPAR gamma/activator proteins binding?…

A: Peroxisome proliferator - activated receptor(PPAR) gamma is a  nuclear receptor of subfamily 1,group…

Q: A certain nonsense suppressor corrects a nongrowingmutant to a state that is near, but not exactly,…

A: A nonsense suppressor mutation can influence the effects of nonsense mutations. It is usually a…

Q: Which phase are initially inhibited by Sic1.Phosphorylation marks Sic1 for ubiquitinylation by…

A: Cell division is the process, in which the cell undergoes parent cell division into daughter cells.

Q: Discuss about Cdc25 phosphataseactivates mitotic CDKs,which activate earlymitotic events

A: The cell cycle, also known as the cell division cycle, is a sequence of events that allow a cell to…

Q: How is the signal generated by binding of TGF-β to cell-surface receptors transmitted to the…

A: TGF-β is a cytokine of the transforming growth factor family of signaling molecules with multiple…

Q: Why would a chromosomal translocation that puts a proto-oncogene under the control of a widely…

A: Please follow step 2 for detailed explanation.

Q: During certain stages of development, the requirement forcertain gene products may require gene…

A: A gene is a stretch of nucleotides present in the DNA. It codes for the synthesis of an RNA or…

Q: What is the effect of supper repressor (lacI^s) mutations?

A: Lac operon is a transcriptionally regulated system in E.coli which enables the bacteria to utilize…

Q: What are the needed materials/molecules of G2 checkpoint?

A: The cell cycle is a highly regulated process. The cell cycle has many checkpoint. Main function of…

Q: What is UPR? What is the downstream impact of UPR activation in an eucaryotic cell?

A: UPR stands for unfolded protein response. It is an intracellular signal transduction pathway that…

Q: How does each of these small GTP-binding proteins contribute to the regulation of cell migration?

A: GTP bonding protein also known as G protein.G protein is present in eukaryotic and classifieds into…

Q: Compare the usual functions of proteins encoded by proto-oncogeneswith those of proteins encoded by…

A: Proteins are macromolecules formed by the long chain of amino acids. They are involved in a wide…

Q: How would you produce a mouse that is homozygous fora rat growth-hormone transgene?

A: Introduction: Transgenic animals are the animals that have had a foreign gene deliberately inserted…

Q: There is now significant evidence to support the existence of cytoneme-mediated delivery of…

A: Cytoneme: it is signalling filopodia that provide conduit for spatial distribution of morphogen.…

Q: Remember that DNA viruses inactivate tumor suppressor genes resulting in cancer. In Burkitt’s…

A: Translocation of c-myc occurs to one of the immunoglobulin foci. This leads to over expression of…

Q: Is the CDK present in G2 checkpoint?

A: Various checkpoints control the cell cycle..

Q: What is diauxic growth? Explain how catabolite repression causes diauxic growth.

A: Introduction  Growth is an important aspect of microbes as they are rapidly dividing species. On an…

Q: The egfr kinase independent transactivation of the ras pathway does require egfr. Explain this…

A: EGFR is a cell surface receptor that binds to certain growth factors and sends signals to the cell's…

Q: What is the effect of having fluctuating cyclin levels throughout the cell cycle, while the levels…

A: Cell cycle  It is a series of events in which cell duplicate it's organelles and divide.

Q: ''In the cellular regulatory pathways that controlcell growth and proliferation, the products of…

A: Cell regulation involves a complex mechanism of different cell signaling pathways that work in a…

Q: Glucocorticolds are steroid hormones that are released into the circulation and will cause changes…

A: The correct option is C

Q: A mutation in the Ras protein renders Ras constitutively active (RasD). What is constitutive…

A: The Ras protein can be referred to as tiny G protein that requires phosphorylation of guanosine…

Q: What intracellular signaling pathway is activated by Ras GTPase?

A: The Ras protein family members belong to a class of protein called small GTPase. They are involved…

Q: When glucose is low and CAMP is present, CAMP's role is to. Activate catabolite activator protein…

A: Ans-When glucose is low and CAMP is present, CAMP's role is to-Activate catabolite activator protein…

Q: What is the duration of G1 checkpoint

A: It includes cell division, replication and growth. All these processes should be carried out in a…

Q: What are positive regulators (activators) and negative regulators (repressors)? Describe.

A: Activators and repressors are two types of gene regulators, with activators causing positive…

Q: why does the activation of M-cdk also result in the activation of Cdc25? What is the mechanism…

A: Cell cycle checkpoints are regulatory systems present in the eukaryotic cell cycle. It guarantees…

Q: what is the role of TERF2 in the deregulation of CDKN1A gene to cause cancer.

A: The basic unit of heredity is the gene, which is a DNA region that codes for a specific protein.…

Q: What processes (besides Complex I and Complex II) contribute QH2 to the Q Cycle of Complex III?

A: The electron transport chain refers to the part of aerobic respiration that occurs in the…

Q: What is the structural difference between normal EGFR and oncogenic receptor, e.g. ERbB? How does it…

A: ErbB is a group of proteins which contains four receptor tyrosine kinases linked to the structure of…

Q: Over-expression of the bcl-2 gene in a cell is likely to be associated with .. a) an increased…

A: A protein that helps govern whether a cell lives or dies by preventing the cell death process known…

Q: Explain with specific examples how oncogenic receptors would promote cellular proliferation in the…

A: Oncogenes are genes which are present in almost all eukaryotic cells especially in higher animals,…

Q: Although slow acting retroviruses lack oncogenes, retroviral infection can activate proto oncogenes…

A: Proto-oncogenes: These are normal cellular genes that help in promoting the proliferation of the…

Q: What is the purpose of the Map Kinase Cascade?

A: Cell signalling is a phenomenon of taking up information from the environment , and crosses through…

Q: List two or three factors that make it advantageous for peptide hor- mones to be synthesized as…

A: Peptide hormones may contain 3 to hundreds of amino acids. They are produced as precursors…

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.