What is alternative splicing of pre-mRNAs?

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter15: From Dna To Protein
Section15.3: Production Of Mrnas In Eukaryotes
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What is alternative splicing of pre-mRNAs?

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When a single pre- mRNA is spliced in more than one way to produce two or more than two mature mRNAs, it is called alternative splicing of pre- mRNA. It results in multiple proteins being encoded by a single gene.

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Alternative splicing is most probably governed by the different conformations of mRNA and few splicing regulators (SR proteins). Alternative splicing occurs differently in different cell types and is regulated by cell type specific factors.

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