What is the phenotype associated with zygotic gene mutations?

Q: Why are chromosomal aberrations considered to have less significance than gene mutations for…

A: Chromosomal aberration refers to the alterations in a number of chromosomes such as loss or gain of…

Q: What are the chances of occurrence of hypermorphic mutation?

A: Mutations are defined as the permanent change in the DNA’s base sequence. The mutation that…

Q: What is PID? What causes it?

A: It consists of primary sex organs called gonads which produce gametes and hormones, secondary sex…

Q: What is the proper route for gene delivery in different kinds of disorders?

A: Gene therapy is a promising method for correcting host pathology by the manipulation of DNA…

Q: What is genomic reduction?

A: The genome size (C-value) is defined as the amount of deoxyribonucleic acid (DNA) in a haploid…

Q: What causes the majority of the mutations found in human melanomas and lung cancer?

A: DNA is the chemical in each cells that makes up the genes and some genes control when cells grow,…

Q: What are the effects of Sxl mutations?

A: Mutations are defined as the change in the sequence of DNA of an organism due to any environmental…

Q: What are the chances of occurrence of neomorphic mutation?

A: Neomorphic mutations are rare dominant gain-of-function mutations that produce a novel phenotype.

Q: How does mutation can affect the central dogma and the phenotype?

A: Mutations are the changes in the DNA sequence. The changes can be single base changes or a fragment…

Q: What is Xenotransplantation ?

A: When organs or tissues are damaged or diseased, they may require repair or replacement. This purpose…

Q: Why do gene mutations not result in chromosomal mutations?

A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…

Q: Can a child typically develop Huntington's Disease even if neither of the parents have the mutated…

A: Huntington's disease (HD) is an inherited disorder that causes nerve cells (called neurons) in parts…

Q: What is the effect of inversion mutation?

A: Mutation is a change in the sequence of genetic material either due to the mistake in replication or…

Q: In Cystic Fibrosis: How is the gene/chromosome affected? How is the cell, tissue, and body systems…

A: Cystic fibrosis is an innate sickness that influences the lungs and stomach related framework. The…

Q: What is the difference between a lesion and an ablation?

A: Cells are the structural and fundamental units of life. Cells that possess similarity in structure…

Q: What is the genetic basis of the symptoms of Down syndrome?

A: Ans: In humans various diseases or disorders are caused by chromosomal aberrations or mutation in…

Q: How would you relate the cancer cellular pathophysiology with genomic instability?

A: Introduction  Cancer is well known disease now a day. In US, 1 in 2 women and 1 in 3 men develops…

Q: What is the chromosome abnormality in cri du chat syndrome?

A: Cri-du-chat syndrome, commonly known as 5p- (5p minus) syndrome. Infants with this syndrome…

Q: What is 18th chromosome abnormality?

A: The chromosomes are the thread like structure that contains hereditary information in the form of…

Q: What is anomic aphasia?

A: The anomia is generally a language disorder - inability to express or communicate. It will slowly…

Q: What is the link between a phosphate functional group, the cellular respiration and the X-linked…

A: A phosphate functional group is a simple phosphorus atom that is bound to four oxygen atoms.…

Q: What occurs during duplication chromosomal mutation?

A: Mutations are defined as sudden heritable change which alters the expression of a gene.

Q: What is the chromosome abnormality in fragile X syndrome?

A: Moderate mental retardation in affected individuals and mild cognitive impairment in affected…

Q: Why don’t all loss-of-function mutations that are recessive at the cellular level behave as…

A: Loss of function mutation refers to the mutation in a gene that leads to reduced or no function of…

Q: What are the possible effects of chromosomal rearrangements?

A: In genetics, a chromosomal rearrangement or Any alternation in the sequence of nucleotide in the…

Q: How Mutations at the Huntington disease locusare caused?

A: Huntington disease is an inherited rare disease that progressively degenerates the nerve cells…

Q: Give the examples of Human Disorders Caused by Single-Gene Mutations ?

A: A single gene disorder is caused by mutations in the DNA sequence of a specific gene or at an…

Q: Why is the incidence of survivable genetic disorders involving deletions of parts of chromosomes so…

A: Deletion is a type of mutation in which a part of DNA molecule is not copied during DNA replication.…

Q: What causes short stature in Turner syndrome?

A: Answer: Introduction: Turner syndrome (TS) is commonly found chromosomal disorders. It appears…

Q: Are mutations that arise during mitosis or meiosis the same?

A: The genetic material consists of a nucleotide sequence that results in the expression of the…

Q: How is the early diagnosis of genetic diseases usually done?

A: Introduction The diagnosis of genetic diseases can be made during the prenatal period, either…

Q: What is a A germline mutation?

A: A germinal mutation or germline mutation as the word indicates itself it is a mutation in germline…

Q: When  germ-line mutations occur ?

A: The alternation in the genome nucleotide sequence of an organism is called a mutation. These are due…

Q: List the three basic categories of chromosome mutations and define each one.

A: Aneuploidy refers to a condition of an abnormal or unusual number of chromosomes. Normally each…

Q: How do orthologous genes arise?

A:

Q: What genotype would a long haired guinea pig have?

A: A genotype is set of heritable genes which can be passed from parents to offsprings.Genotype is the…

Q: Explain maternal-effect mutations?

A: Mutation means sudden changes occur in DNA sequences. The mutation occurs randomly. It also occurs…

Q: What are the causes affecting by genetic disorders?

A: BASIC INFORMATION GENETIC DISORDER It is the disorder which are inherited from one generation to…

Q: When Replacement of the original gene occurs ?

A: A gene is the essential physical and functional unit of heredity. They are comprised of DNA…

Q: What are three similarities and three differences between Germline mutations and Somatic mutations?

A: A mutation refers to the alteration in the sequence of DNA (deoxyribonucleic acid). It can be a…

Q: What is retrograde?

A: Introduction  The proteins which are formed by the ribosomes attached over the ER are transported to…

Q: Which type of mutation is responsible for new variations of a trait?

A: Any alteration in the sequence of DNA of a gene can cause changes in the resulting protein in such a…

Q: What is mutation? Distinguish between (i) neutral and silent mutation (ii) germ line and somatic…

A: Mutations can sometimes be beneficial, when they result in traits that will benefit the organism.…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.