Asked Mar 26, 2019

What kinds of infections do prions cause and what part of the human body is usually affected?


Expert Answer

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Step 1

Prions are the disease-causing agents, that are made up of the protein named prion. They are without the genetic material, that is, RNA or DNA. They contain the misfolded protein. Moreover, if they reside in any host, then they misfold the host’s protein and cause the diseases. The aggregates of prions are stable, and accumulate in the infected tissue, causing cell death.

Step 2

There are various infection and diseases caused by the prions, as they misfold the proteins present in the host’s body. These diseases are as follows:

  1. CJD (Creutzfeldt-Jakob disease) – It is of two types – familial CJD and sporadic CJD. The sporadic CJD is caused due to the prions, that infect the tissues of the
  2. Variant CJD – It is caused by humans if they eat the meat of an infected cow. This infection causes the normal human prion protein to act abnormally.
  3. Kuru – It is seen mai...

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