What would most likely occur to nuclear import if the GTPase Activating Protein of RAN was inhibited by a drug? Nuclear import would still occur and cargo would be released Proteins with an NLS sequence would not bind the importin complex Cargo would not be released from the importin complex The importin complex would not form The importin-protein complex would not interact with the nuclear pore

What would most likely occur to nuclear import if the GTPase Activating Protein of RAN was inhibited by a drug? Nuclear import would still occur and cargo would be released Proteins with an NLS sequence would not bind the importin complex Cargo would not be released from the importin complex The importin complex would not form The importin-protein complex would not interact with the nuclear pore

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter6: Cell Communication

Section: Chapter Questions

Problem 4TYU

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Similar questions

"In the regulation of molecular switches, protein kinases and guanine nucleotide exchange factors (GEFs) always turn proteins on, whereas protein phosphatases and GTPase activating proteins (GAPS) always turn proteins off" is true or false.
What would happen to nuclear transport if you removed all of the Ran-GAP? For a while nuclear import receptors will still deliver cargo to the inside of the nucleus Nuclear import receptors will be loaded with RanGTP and will gradually stop binding to the proteins with NLS signals Nuclear export receptors will no longer deliver their cargo to the outside of the membrane and will probably shuttle in and out of the nucleus full of cargo Ran-GDP will no longer be made All of the above
Which of the following is a type of signal transduction pathway controlling gene expression? All of these Protein subunit dissociation pathway Receptor-associated kinase pathway None of these Cytosolic kinase pathway
An enzyme-linked receptor (a) is a cytoplasmic protein (b) would not be found on plant cell surfaces (c) forms a dimer with another enzyme-linked receptor when a ligand binds to it (d) is typically an adenylyl cyclase molecule(e) typically activates ion channels
Your roommate’s summer research project is to identify drugs that interfere with nuclear import. She identifies a drug that inhibits the ability of Ran to exchange GDP for GTP. What effect does this drug have on nuclear import? Describe where cargo protein Z would be found after it is synthesized in the cytosol.
A scientist engineered a set of genes, each encoding a protein with two conflicting signal sequences. If the genes were expressed in a cell, predict which signals are preferred to be used and explain your choices. The sequence: a) C-terminal, signal for import into nucleus, signal for import into ER, N-terminal. b) C-terminal, signal for retention in ER, signal for import into mitochondria, N-terminal. c) Has signal for import into nucleus and signal for export from nucleus.
Which is true of both internal signal-anchor sequences and nuclear localization signals? interact with/bind to SRP (signal recognition particle) are exactly the same (consensus) sequence in every protein are composed of hydrophobic amino acids can be found anywhere within a protein’s primary structure
Which of the following elements may be in the transduction part of cell signaling? Select one: a. A phosphatase b. A kinase c. cyclin AMP d. ions e. All answers are correct
Protein phosphorylation is commonly involved with all of thefollowing except(A) activation of receptor tyrosine kinases.(B) activation of protein kinase molecules.(C) activation of G protein-coupled receptors.(D) regulation of transcription by signaling molecules.
ADH causes cells of the kidneys to insert aquaporins (leak channels for water) into their membranes. It most likely does this by: Group of answer choices A. activating a second messenger system that leads to activation/insertion of the aquaporin B. binding to DNA adjacent to genes that code for enzymes that make aquaporins C. binding to genes adjacent to those that code for aquaporins and increasing their production D. directly phosphorylating the aquaporins
which of the followinf would a MAPKK (MAP2K) protein would be activated (phosphorylated) by? a. MAPK b. RTK c. MAPKKK d. MAPKK
Which of the following would be considered second messengers of a signaling pathway? Select one: a. A kinase enzyme b. A scaffolding protein holding three kinases c. Adenyl cyclase d. All answers are examples of second messengers e. A sugar like inositol f. Ligand gated channel